Publications
Original Research Articles
2010
Steimel A, Wong L, Najarro EH, Ackley BD, Garriga G, Hutter H.
The Flamingo ortholog FMI-1 controls pioneer-dependent navigation of follower axons in C. elegans
Development 137(21):3663-73 (2010)
Ash PE, Zhang YJ, Roberts CM, Saldi T, Hutter H, Buratti E, Petrucelli L, Link CD
Neurotoxic effects of TDP-43 overexpression in C. elegans
Hum Mol Genet. 19(16):3206-18 (2010)
Park JO, Pan J, Möhrlen F, Schupp MO, Johnsen R, Baillie DL, Zapf R, Moerman DG, Hutter H.
Characterization of the astacin family of metalloproteases in C. elegans
BMC Dev Biol. 10:14 (2010)
2009
Hutter, H., Ng M-P., Chen, N.
GExplore: a web server for integrated queries of protein domains, gene expression and mutant phenotypes
BMC Genomics 10, 529 (2009)
Schlotterer A, Kukudov G, Bozorgmehr F, Hutter H, Du X, Oikonomou D, Ibrahim Y, Pfisterer F, Rabbani N, Thornalley P, Sayed A, Fleming T, Humpert P, Schwenger V, Zeier M, Hamann A, Stern D, Brownlee M, Bierhaus A, Nawroth P, Morcos M.
C. elegans as model for the study of high glucose mediated lifespan reduction
Diabetes 58(11):2450-6 (2009)
Almedom RB, Liewald JF, Hernando G, Schultheis C, Rayes D, Pan J, Schedletzky T, Hutter H, Bouzat C, Gottschalk A.
An ER-resident membrane protein complex regulates nicotinic acetylcholine receptor subunit composition in Caenorhabditis elegans
EMBO Journal 28(17):2636-49 (2009)
Schwarz, V., Pan, J., Voltmer-Irtsch, S., Hutter, H.
IgCAMs redundantly control axon navigation in C. elegans
Neural Development 4:13 (2009)
2008
Ikeda DD, Duan Y, Matsuki M, Kunitomo H, Hutter H, Hedgecock EM, Iino Y
CASY-1, an ortholog of calsyntenins/alcadeins, is essential for learning in Caenorhabditis elegans
PNAS 105(13):5260-5 (2008)
Schmitz C, Wacker I, Hutter H
The Fat-like cadherin CDH-4 controls axon fasciculation, cell migration, hypodermis and pharynx development in Caenorhabditis elegans
Dev.Biol. 316(2):249-59 (2008)
Morcos M, Du X, Pfisterer F, Hutter H, Sayed AA, Thornalley P, Ahmed N, Baynes J, Thorpe S, Kukudov G, Schlotterer A, Bozorgmehr F, El Baki RA, Stern D, Moehrlen F, Ibrahim Y, Oikonomou D, Hamann A, Becker C, Zeier M, Schwenger V, Miftari N, Humpert P, Hammes HP, Buechler M, Bierhaus A, Brownlee M, Nawroth PP.
Glyoxalase-I Reduces Mitochondrial Reactive Oxygen Production and Enhances Life Span in C. elegans
Aging Cell 7(2):260-9 (2008)
Wang X, Cheever T, Zhang W, Schwarz V, Opperman K, Ecklund J, Hutter H, Koepp D, Chen L
The C. elegans L1CAM homologue, LAD-2, functions as a co-receptor in MAB-20/Sema2-mediated axon guidance
J. Cell Biology 180(1):233-246 (2008)
2007
Hrus A, Lau G, Hutter H, Schenk S, Ferrall J, Brown-Luedi M, Chiquet-Ehrismann R, and Canevascini S
C. elegans agrin is expressed in pharynx, IL1 neurons and distal tip cells and does not genetically interact with genes important for synaptogenesis or muscle function
PLoS One 2(8), e731 (2007)
Brandt R, Gergou A, Wacker I, Fath T and Hutter H
A Caenorhabditis elegans model of tau hyperphosphorylation: Induction of developmental defects by transgenic overexpression of Alzheimer’s disease-like modified tau
Neurobiology of Aging, 30(10:22-33 (2009); epub June 21, 2007
Diogon M, Nagamatsu Y, Sookhareea S, Landmann F, Hutter H, Vitale N, and Labouesse M
The RhoGAP RGA-2 and LET-502/ROCK achieve a balance of actomyosin-dependent forces in the C. elegans epidermis to control morphogenesis
Development 134(13): 2469-79 (2007)
Fielenbach N, Neubert K, Chan T, Hutter H, Guardavaccaro D, Pagano M and Antebi A
DRE-1: an evolutionary conserved F box protein that regulates C. elegans developmental age
Dev. Cell 12(3):443-55 (2007)
Schmitz C, Kinge P and Hutter H
Axon guidance genes identified in a large scale RNAi screen using the RNAi-hypersensitive Caenorhabditis elegans strain nre-1(hd20) lin-15(hd126)
PNAS 104(3), 834-9 (2007)
2006
Blanchard D, Hutter H, Fleenor J and Fire A
A differential cytolocalization assay for analysis of macromolecular assemblies in the eucaryotic cytoplasm
Mol. Cell. Proteomics, 5(11), 2175-84 (2006)
Dong C, Muriel JM, Ramirez S, Hutter H, Hedgecock EM, Breydo L, Baskakov IV and Vogel BE
Hemicentin assembly in the extracellular matrix is mediated by Distinct Structural Modules
J. Biol Chem., 281(33), 23606-23610 (2006)
Schnabel R, Bischoff M, Hintze A, Schulz AK, Hejnol A, Meinhardt H and Hutter H
Global cell sorting in the C. elegans embryo defines a new mechanism for pattern formation.
Developmental Biology 294: 418-431 (2006)
Schmid C, Schwarz V and Hutter, H
AST-1, a novel ETS-box transcription factor, controls axon guidance and pharynx development in C. elegans.
Developmental Biology 293(2): 403-413 (2006)
Abraham C, Hutter H, Palfreyman MT, Spatkowski G, Weimer RM, Windoffer R, Jorgensen EM and Leube RE
Synaptic tetraspan vesicle membrane proteins are conserved but not needed for synaptogenesis and neuronal function in Caenorhabditis elegans.
Proc Natl Acad Sci U S A 103(21): 8227-8232 (2006)
2005
Muriel JM, Dong C, Hutter H and Vogel BE
Fibulin-1C and Fibulin-1D splice variants have distinct functions and assemble in a hemicentin-dependent manner.
Development 132(19):4223-34 (2005)
Hutter H, Wacker I, Schmid C and Hedgecock EM
Novel genes controlling ventral cord asymmetry and navigation of pioneer axons in C. elegans
Developmental Biology 284(1):260-72 (2005)
2004
Yankowitz JL, Shakir MA, Hedgecock EM, Hutter H, Fire A and Lundquist EA
UNC-39, the C. elegans homolog of the human myotonic dystrophy-associated homeodomain protein Six5, regulates cell motility and differentiation
Developmental Biology, 272, 389-402 (2004)
Ludewig AH, Kober-Eisermann C, Weitzel C, Bethke A, Neubert K, Gerisch B, Hutter H and Antebi, A.
A novel nuclear receptor/coregulator complex regulates C. elegans lipid metabolism, larval development and aging
Genes and Development, 18, 2120-2133 (2004)
Hutter H
Five-color in vivo imaging of neurons in C. elegans with fluorescent proteins
Journal of Microscopy, 215, 213-218 (2004)
2003
Möhrlen F, Hutter H and Zwilling R.
The astacin protein family in C. elegans
European Journal of Biochemistry 270, 4909-4920 (2003)
Hutter H
Extracellular cues and pioneers act together to guide axons in the ventral cord of C. elegans
Development 130: 5307-18 (2003)
Wacker I, Schwarz V, Hedgecock EM and Hutter H
zag-1, a zinc-finger-homeobox transcription factor controlling neuronal differentiation and axon outgrowth in C. elegans
Development 130: 3795-3805 (2003)
Huang C, Hall DH, Karantza-Wadsworth V, Vogel BE, Hutter H, Kao G, Hedgecock EM, Yurchenco PD and Wadsworth WG
Segregation of the laminin a subunits to sites where basement membranes assemble in C. elegans
Development 130: 3343-3358 (2003)
2000-2002
Hutter H
New ways to look at axons in Caenorhabditis elegans.
Microscopy Research and Technique 48: 47-54 (2000).
Hutter H, Vogel BE, Plenefisch JD, Norris CR, Guo C, Proenca RB, Zhu X, Scheel J and Hedgecock EM
Conservation and Novelty in the Evolution of Cell Adhesion and Extracellular Matrix Genes.
Science 287: 989-994 (2000)
1996-1999
Schnabel R, Hutter H, Moerman D and Schnabel H
Assessing normal embryogenesis in Caenorhabditis elegans using a 4D microscope: variability of development and regional specification.
Developmental Biology 184: 234-265 (1997)
Schnabel R, Weigner C, Hutter H, Feichtinger R and Schnabel H
mex-1 and the general partitioning of cell fate in the early C. elegans embryo.
Mechanisms of Development 54: 133-147 (1996).
Moerman DG, Hutter H, Mullen GP and Schnabel R
Cell autonomous expression of perlecan and plasticity of cell shape in embryonic muscle of C. elegans.
Developmental Biology 173: 228-242 (1996)
1992-1995
Hutter H and Schnabel R
Establishment of left-right asymmetry in the C. elegans embryo: a multistep process involving a series of inductive events.
Development, 121: 3417-3425 (1995)
Hutter H and Schnabel R
Specification of anterior-posterior differences within the AB lineage in the C. elegans embryo: a polarising induction.
Development 121: 1559-1568 (1995)
Hutter H and Schnabel R
glp-1 and inductions establishing embryonic axes in the C. elegans embryo.
Development 120: 2051-2064 (1994)
Review articles
Morcos M. and Hutter, H.
The Model Caenorhabditis elegans in Diabetes Mellitus and Alzheimer’s Disease
Journal of Alzheimer’s Disease, 16(4):897-908 (2009)
Book chapters
Hutter H
Fluorescent reporter methods.
in C. elegans: Methods and Apllications (ed. K. Strange), pp. 157-176
Humana Press, Totowa, NJ, 2006