Baillie Lab

• Simms et al. A strawberry notch homolog, let-765/nsh-1, positively regulates lin-3/egf expression to promote RAS-dependent vulval induction in C. elegans.
  Dev Biol 2010
• Mah et al. Characterization of the octamer, a cis-regulatory element that modulates excretory cell gene-expression in Caenorhabditis elegans.
  BMC Mol Biol 2010
• Jones et al. Quality High resolution molecular analysis of deficiencies affecting recombination in C. elegans.
  Mol Genet Genomics 2009

Beh Lab

• Fei et al. Genome-wide analysis of sterol-lipid storage and trafficking in Saccharomyces cerevisiae.
  Eukaryot Cell 2008
• Kozminski et al. Homologues of oxysterol-binding proteins affect Cdc42p- and Rho1p-mediated cell polarization in Saccharomyces cerevisiae.
  Traffic 2006
• Baumann et al. Transport of newly synthesized sterol to the sterol-enriched plasma membrane occurs via nonvesicular equilibration.
  Biochemistry 2005

Brandhorst Lab

• Bishop, C.D., and B.P. Brandhorst. Development of nitric oxide synthase-defined neurons in the sea urchin larval ciliary band and evidence for a chemosensory function during metamorphosis.
  Dev Dyn 2007
• Burke et al. A genomic view of the sea urchin nervous system.
  Devel Biol 2006
• Bishop, C.D., and B.P. Brandhorst. On nitric oxide signaling, metamporphosis, and the evolution of life cycles.
  Evol Dev 2003

Brinkman Lab

• Winstanley et al. Newly introduced genomic prophage islands are critical determinants of in vivo competitiveness in the Liverpool Epidemic Strain of Pseudomonas aeruginosa.
  Genome Res 2009
• Bovine Genome Sequencing and Analysis Consortium. The genome sequence of taurine cattle: a window to ruminant biology and evolution.
  Science 2009
• Lynn et al. Facilitating Systems Level Analyses of the Mammalian Innate Immune Response.
  Mol Syst Biol 2008

Brockman Lab

• Berger et al. Viral adaptation to immune selection pressure by HLA class I-restricted CTL responses targeting epitopes in HIV frameshift sequences.
  J Exp Med 2010
• Brockman et al.IL-10 is up-regulated in multiple cell types during viremic HIV infection and reversibly inhibits virus-specific T cells.
  Blood 2009
• Miura et al.HLA-associated alterations in replication capacity of chimeric NL4-3 viruses carrying gag-protease from elite controllers of human immunodeficiency virus type 1.
  J Virol 2009

Chen Lab

• Chu JSC, Baillie DL, Chen N. Convergent evolution of RFX transcription factors and ciliary genes predated the origin of metazoans.
  BMC Evol Biol 2010
• Vergara et al. Polymorphic segmental duplication in the nematode Caenorhabditis elegans.
  BMC Genomics 2009
• She R, Chu JSC, Wang K, Pei J, Chen N. genBlastA: enabling BLAST to identify homologous gene sequences.
  Genome Res 2009

Choy Lab

• Choy JC .Granzymes in solid organ transplant rejection.
  Cell Death and Diff 2010
• Choy JC and Pober JS. Paracrine generation of NO by bystander human CD8 T cells augments allogeneic responses by inhibiting cytokine deprivation-induced cell death.
  Am J Transplant 2009
• Choy et al. Induction of inducible NO synthase in bystander human T cells increases allogeneic responses in the vasculature.
  Proc Natl Acad Sci USA 2007

Cornell Lab

• Lee J, Johnson J, Ding Z, Paetzel M, Cornell RB. Phosphoninositide 3-kinase regulates plasma membrane targeting of Ras-specific exchange factor RasGRp1.
  J Biol Chem 2011
• Taneva et al. Contribution of Each Membrane Binding Domain of the CTP:Phosphocholine Cytidylyltransferase-alpha Dimer to Its Activation, Membrane binding, and Membrane Cross-bridging.
  J Biol Chem 2008

Craig Lab

• Megli, et al.Crystal structure of the Vibrio choleraecolonization factor TcpF and identification of a functional immunogenic site.
  J Mol Biol 2011
• Lim et al. Vibrio cholerae El Tor TcpA crystal structure and mechanism for pilus-mediated microcolony formation.
  Mol Microbiol 2010
• Li et al. Vibrio cholerae toxin-coregulated pilus structure analyzed by hydrogen/deuterium exchange mass spectrometry.
  Structure 2008

Davidson Lab

• Phillips et al. Assignment of Atlantic salmon (Salmo salar) linkage groups to specific chromosomes: Conservation of large syntenic blocks corresponding to whole chromosome arms in rainbow trout (Oncorhynchus mykiss).
  BMC Genet 2009
• Davidson et al. The Sex Determining Loci and Sex Chromosomes in the Family Salmonidae.
  Sex Dev 2009
• Johnstone et al. Genomic Organization and Evolution of the Vomeronasal Type 2 Receptor-Like (OlfC) Gene Clusters in Atlantic Salmon, Salmo salar.
  Mol Biol Evol 2009

Gorski Lab

• Chittaranjan et al. Steroid hormone control of cell death and cell survival: molecular insights using RNAi.
  PLoS Genet 2009
• Hou et al. Effector caspase Dcp-1 and IAP protein Bruce regulate starvation-induced autophagy during Drosophila melanogaster oogenesis.
  J Cell Biol 2008
• Qadir et al. Macroautophagy inhibition sensitizes tamoxifen-resistant breast cancer cells and enhances mitochondrial depolarization.
  Breast Cancer Res Treat 2008

Harden Lab

• Bahri et al. The leading edge during dorsal closure as a model for epithelial plasticity: Pak is required for recruitment of the Scribble complex and septate junction formation.
  Development 2010
• Zahedi et al. Leading edge-secreted Dpp cooperates with ACK-dependent signaling from the amnioserosa to regulate myosin levels during dorsal closure.
  Dev Dyn 2008
• Conder et al. The serine/threonine kinase dPak is required for polarized assembly of F-actin bundles and apical-basal polarity in the Drosophila follicular epithelium.
  Dev Biol 2007

Hawkins Lab

• Hingwing et al. CWN-1 functions with DSH-2 to regulate C. elegans asymmetric neuroblast division in a β-catenin independent Wnt pathway.
  Dev Biol 2009
• King et al. The N- or C-terminal domains of DSH-2 can activate the C. elegans Wnt/β-catenin asymmetry pathway.
  Dev Biol 2009

Holt Lab

• Warren RL, Holt RA. A census of predicted mutational epitopes suitable for immunologic cancer control.
  Hum Immunol 2010
• Mead et al. Cytosolic protein interactions of the schizophrenia susceptibility gene dysbindin.
  J Neurochem 2010
• Freeman et al. Profiling the T-cell receptor beta-chain repertoire
  by massively parallel sequencing.
  Genome Res. 2009

Honda Lab

• Sinclair et al.Drosophila O-GlcNAc transferase (OGT) is encoded by the Polycomb group (PcG) gene, super sex combs (sxc). .
  Proc Natl Acad Sci USA 2009
• Hallson et al. The Drosophila cohesin subunit Rad21 is a trithorax group (trxG) protein.
  Proc Natl Acad Sci 2008
• Schulze et al.  Heterochromatic genes in Drosophila: a comparative analysis of two genes.
  Genetics 2006

Jones Lab

• Diguistini et al. De novo genome sequence assembly of a filamentous fungus using Sanger, 454 and Illumina sequence data.
  Genome Biol 2009
• Birol et al. De novo transcriptome assembly with ABySS.
  Bioinformatics 2009
• Robertson et al. Genome-wide relationship between histone H3 lysine 4 mono- and tri-methylation and transcription factor binding.
  Genome Res 2008

Leroux Lab

• Williams et al. MKS and NPHP modules cooperate to establish basal body/transition zone membrane associations and ciliary gate function during ciliogenesis.
  J Cell Biol 2011
• Huang et al. TMEM237 is mutated in individuals with a Joubert syndrome related disorder and expands the role of the TMEM family at the ciliary transition zone.
  Am J Hum Genet 2011
• Jensen et al. Localization of a guanylyl cyclase to chemosensory cilia requires the novel ciliary MYND domain protein DAF-25.
  PLoS Genet 2010

Paetzel Lab

• Nam et al. Crystal structure of Bacillus subtilis signal peptide peptidase A.
  J Mol Biol 2012
• Kim et al. Crystal structure of the beta-barrel assembly machinery BamCD complex.
  J Biol Chem 2011
• Chung & Paetzel Crystal structure of a viral protease intramolecular acyl-enzyme complex. Insights into cis-cleavage at the VP4/VP3 junction of Tellina birnavirus.
  J Biol Chem 2011

Pio Lab

• Yan et al. RPA nucleic acid-binding properties of IFI16-HIN200.
  Biochim Biophys Acta 2008
• Dalal K, Pio F. Thermodynamics and stability of the PAAD/DAPIN/PYRIN domain of IFI-16.
  FEBS Lett 2006

• Cooper et al. Aedes Dronc: a novel ecdysone-inducible caspase in the yellow fever mosquito, Aedes aegypti.
  Insect Mol Biol 2007

Quarmby Lab

• Parker et al. Centrioles are Freed From Cilia by Severing Prior to Mitosis.
  Cytoskeleton 2010
• Rasi et al. Katanin Knockdown Supports a Role for Microtubule Severing in Release of Basal Bodies before Mitosis in Chlamydomonas.
  Mol Biol Cell 2009
• Hilton et al. The NIMA-related kinase NEK1 cycles through the nucleus.
  Biochem Biophys Res Commun 2009

Scott Lab

• van Houten et al. Engineering filamentous phage carriers to improve focusing of antibody
  responses against peptides.
  Vaccine 2010
• Montero et al. The Membrane-Proximal External Region of the Human Immunodeficiency Virus Type 1 Envelope: Dominant Site of Antibody Neutralization and Target for Vaccine Design.
  Microbiol Mol Biol Rev 2008
• Scott JK, Smith GP. Searching for peptide ligands with an epitope library.
  Science 1990

Sen Lab

• Huang Y.C. and Sen D. A contractile electronic switch made of DNA. 
  J Am Chem Soc 2010
• Lee H.W. et al. Reversible Photo-Regulation of a Hammerhead Ribozyme using a Diffusible Effector.
  J Mol Biol 2007
• Chinnapen, D. J.-F. and Sen, D. A Deoxyribozyme that Harnesses Light to Repair Thymine Dimers in DNA. 
  Proc Natl Acad Sci USA 2004

Thewalt Lab

• Hsueh et al. Deuterium NMR study of the effect of ergosterol on POPE membranes.
  Biophys J 2010
• Sikor et al. Interaction of a charged polymer with zwitterionic lipid vesicles.
  Langmuir 2010
• Goni et al. Phase diagrams of lipid mixtures relevant to the study of membrane rafts.
  Biochim Biophys Acta. 2008

Unrau Lab

• Lau MW, Unrau PJ. A promiscuous ribozyme promotes nucleotide synthesis in addition to ribose chemistry.
  Chem Biol 2009
• Morin et al. Comparative analysis of the small RNA transcriptomes of Pinus contorta and Oryza sativa.
  Genome Res 2008
• Zaher et al.Selection of an improved RNA polymerase ribozyme with superior extension and fidelity.
  RNA 2007

Verheyen Lab

• Lee et al. Homeodomain-interacting protein kinases (Hipks) promote Wnt/Wg signaling through stabilization of beta-catenin/Arm and stimulation of target gene expression.
  Development 2009
• Lee et al. Hipk is an essential protein that promotes Notch signal transduction in the Drosophila eye by inhibition of the global co-repressor Groucho.
  Dev Biology 2009
• Braid and Verheyen. Drosophila nemo promotes eye specification directed by the retinal determination gene network.
  Genetics 2008

Young Lab

• Chan et al. Bimodal agonism in heteromeric cyclic nucleotide-gated channels.
  Channels (Austin) 2009
• Wicks et al. Sensitivity of HCN channel deactivation to cAMP is amplified by an S4 mutation combined with activation mode shift.
  Channels (Austin) 2009
• Wicks et al. The cytoplasmic cAMP-sensing domain of pacemaker HCN channels uses two structurally distinct mechanisms to regulate voltage-gating. [Refereed presentation]
  Circulation 120: S664 2009