Pradhan-Sundd, T. and E.M. Verheyen (2015) The Myopic-Ubpy-Hrs nexus enables endosomal recycling of Frizzled. Molecular Biology of the Cell, e-pub.

Fernandes, V.M., Pradhan-Sundd, T., Blaquiere, J. and E.M. Verheyen (2015) Ras/MEK/MAPK-mediated regulation of heparin sulfate proteoglycans promotes retinal fate in the Drosophila eye-antennal disc. Developmental Biology, 402: 109-118. Also featured on the cover!

Swarup, S., Pradhan-Sundd, T. and E.M. Verheyen (2015) Genome-wide in vivo identification of kinases and phosphatases that regulate Wnt signaling. Development,142 :1502-1515.


Fernandes, V.M., McCormack, K., Lewellyn, L. and E.M. Verheyen (2014) Integrins regulate apical constriction via microtubule stabilization in the Drosophila eye disc epithelium. Cell Reports, 9(6): 2043-55. Also featured on the cover!

Fernandes, V.M., Braid, L.R. and E.M. Verheyen (2014) Nemo is a conserved core proneural target involved in Notch-mediated lateral inhibition during neurogenesis. Developmental Biology, 392: 334-343.

Pradhan-Sundd, T. and E.M. Verheyen (2014) The role of Bro1 domain-containing protein Myopic in endosomal trafficking of Wnt/Wingless. Developmental Biology, 392: 93-107. Also featured on the cover!

Blaquiere, J., Lee, W. and E.M. Verheyen (2014) Homeodomain-interacting protein kinase promotes normal and ectopic eye development through repression of twin of eyeless and eyeless. Developmental Biology, 390:14–25.  Also featured on the cover!


This article in Science Signaling features our work on Hipk and the Hippo pathway (Chen and Verheyen, 2012).


Chen, J. and E.M. Verheyen (2012) Homeodomain-interacting protein kinase regulates Yorkie activity to promote tissue growth. Current Biology, 22(17):1582-6.

Verheyen, E.M., Swarup, S. and W. Lee (2012) Hipk proteins dually regulate Wnt/Wingless signal transduction. Fly 6(2): 126-131.

Swarup, S. and E.M. Verheyen (2012) Wnt/Wingless signaling in Drosophila. CSH Perspectives, 4(6). pii: a007930.

Morillo, S.A., Braid, L.R., Verheyen #, E.M. and I. Rebay # (2012) Nemo phosphorylates Eyes absent and enhances output from the Eya-Sine oculis transcriptional complex during Drosophila retinal determination. Developmental Biology, 365(1):267-76. # joint corresponding authors.


Swarup, S. and E.M. Verheyen (2011) Drosophila homeodomain-interacting protein kinase inhibits the Skp1-Cul1-F-box E3 ligase complex to dually promote Wingless and Hedgehog signaling. Proc. Natl. Acad. Sci. USA, 108 (24): 9887-9892.

Mirkovic, I., Gault, W.J.*, Rahnama, M.*, Jenny, A.*, Gaengel, K., Bessette, D., Gottardi, C.J., Verheyen, E.M.# and M. Mlodzik# (2011) The Nemo kinase phosphorylates β-catenin to promote ommatidial rotation and connects core PCP factors to E-cadherin/β-catenin. Nature Structural & Molecular Biology 18: 665–672. # joint corresponding authors, * joint second authors.


Verheyen, E.M. and H. Clevers (2010) Wnts as self-renewal factors: mammary stem cells and beyond. Cell Stem Cell 6: 494-495. (A preview of a Cell Stem Cell paper written by my former PhD student Arial Zeng and Roel Nusse).

Braid, L.R.*, Lee, W.*, Uetrecht, A.C., Swarup, S., Papaianni, G., Heiler, A. and E.M. Verheyen (2010) Nemo phosphorylates Even-skipped and promotes Eve-mediated repression of odd-skipped in even parasegments during Drosophila embryogenesis.  Developmental Biology 343(1-2):178-89.  *joint first authors.

Verheyen, E.M. and C.J. Gottardi (2010) Regulation of Wnt/beta-catenin signaling by protein kinases.  Developmental Dynamics 239(1):34-44.


Merino, C., Penney, J., González, M., Tsurudome, K., Moujahidine, M., O’Connor, M.B., Verheyen, E.M. and P. Haghighi (2009) Nemo kinase interacts with Mad to coordinate synaptic growth at the Drosophila NMJ. Journal of Cell Biology 185(4): 713-25.

Lee, W., Swarup, S., Chen, J., Ishitani, T. and E.M. Verheyen (2009b) Homeodomain-interacting protein kinases (Hipks) promote Wnt/Wg signaling through stabilization of β-catenin/Arm and stimulation of target gene expression. Development 136: 241-251.

Lee, W., Andrews, B.C., Faust, M., Walldorf, U. and E.M. Verheyen (2009a) Hipk is an essential protein that promotes Notch signal transduction in the Drosophila eye by inhibition of the global co-repressor Groucho. Developmental Biology 325: 263-272.


Zeng, Y.A.*, Rahnama, M.*, Wang, S., Lee, W. and E.M. Verheyen (2008) Inhibition of Wg signaling through activated BMP involves competition between Mad and Armadillo/β-catenin for dTcf binding. PLoS ONE 3(12): e3893. *joint first authors.

Braid, L.R. and Verheyen, E.M. (2008) Drosophila Nemo Promotes Eye Specification Directed by the Retinal Determination Gene Network.  Genetics 180: 283-299.


Verheyen, E.M. (2007) Opposing effects of Wnt and MAPK on BMP/Smad signal duration.  Developmental Cell 13: 755-756.

Zeng, Y.A.*, Rahnama, M.*, Wang, S., Sosu-Sedzorme, W. and E.M. Verheyen (2007) Drosophila Nemo/Nlk antagonizes Bone Morphogenetic Protein signalling by phosphorylation of Mad and inhibition of its nuclear accumulation. Development 134: 2061-2071,  *joint first authors. 



Zeng, Y.A. and Verheyen, E.M. (2004) Nemo is an inducible antagonist of Wingless signaling during Drosophila wing development. Development 131: 2911-2920.


Mirkovic, I.,Charish, K., Gorski, S.M., McKnight, K., and Verheyen, E.M. (2002) Drosophila nemo is an essential gene involved in the regulation of programmed cell death. Mechanisms of Development 119: 9-20. 2002 Mirkovic et al.pdf

MacLean, S.J., Andrews, B.C., and Verheyen, E.M. (2002) Characterization of Dir: a putative potassium inward rectifying channel in Drosophila.
Mechanisms of Development 116: 193-197. 2002 Maclean et al.pdf


Verheyen, E.M., Mirkovic, I., MacLean, S.J., Langmann, C., Andrews, B.C., and MacKinnon, C. (2001) The tissue polarity gene nemo carries out multiple roles in patterning during Drosophila development. Mechanisms of Development 101: 119-132. 2001 Verheyen et al.pdf