Fall 2016 - CHEM 180 D100
The Chemistry of Life (3)
Class Number: 4030
Delivery Method: In Person
Course Times + Location:
Mo, We, Fr 9:30 AM – 10:20 AM
AQ 5018, Burnaby
Exam Times + Location:
Dec 14, 2016
12:00 PM – 3:00 PM
AQ 3149, Burnaby
1 778 782-7661
A basic introduction to chemical kinetics, thermodynamics, electrochemistry, and equilibria as they apply to the structure and function of biomolecules. Concepts will be illustrated using modern examples of biological systems. Students will be introduced to central ideas and selected molecular engineering methods in biochemistry and molecular biology.
3 lecture hours/week; 1 tutorial hour/week
1. Organic Molecules (≈ 3 Lectures)
Drawing organic molecules
Geometry of bonds and bond lengths
2. Thermodynamics (≈ 4 Lectures)
Three laws, definitions
Gibbs free energy, spontaneity
3. Chemical Equilibria and Acids/Bases (≈ 5 Lectures)
Le Chatelier's principle
Kw, Keq, pH, pKa
Ionization of amino acid residues
4. Chemical Kinetics (≈ 5 Lectures)
Reaction coordinate diagrams
Basic rate equations
5. Intoduction to Biomolecules (≈ 5 Lectures)
Functional localization of Biomolecules
6. Central Dogma of Molecular Biology (≈ 4 Lectures)
Structure of cells
Flow of information in central dogma
Location and significance of molecules
7. Nervous System (≈ 9 Lectures) (Integrated Topics)
Oxidation and reduction
Potential difference / membrane potential
Neuron cell structure
Chemical Neurotransmitters (Acetylcholine)
Proteins as machines that perform work
COURSE-LEVEL EDUCATIONAL GOALS:
- To give engineering students who have taken CHEM 121-4 General Chemistry and Laboratory I sufficient background to enter KIN 208-3 Introduction to Physiological Systems.
- To give science or engineering students who have CHEM 121, but no background in biology, a basic understanding of central concepts of bioorganic chemistry and biochemistry.
- Problem Sets 25%
- Midterm Exam 30%
- Final Exam 45%
Notes are provided in class.
Lecture allocated to each topic are an estimate and may vary slightly.
MATERIALS + SUPPLIES:
John Kuriyan, Boyana Konforti & David Wemmer. The Molecules of Life. 2012. Publisher: Garland Science.
Charlotte Pratt & Kathleen Cornely. Essential Biochemistry. 2004. Publisher: Wiley.
Donald Voet & Judith G. Voet. Biochemistry. 1990. Publisher: Wiley.
Bruce Alberts et al. The Molecular Biology of the Cell. 1983. Publisher: Garland Science.
Harvey Lodish et al. Molecular Cell Biology. 2000. Publisher: W. H. Freeman.
Department Undergraduate Notes:
A grade of C- or better is required for all prerequisite courses.
SFU’s Academic Integrity web site http://students.sfu.ca/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating. Check out the site for more information and videos that help explain the issues in plain English.
Each student is responsible for his or her conduct as it affects the University community. Academic dishonesty, in whatever form, is ultimately destructive of the values of the University. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the University. http://www.sfu.ca/policies/gazette/student/s10-01.html
ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS