Spring 2016 - MBB 427 D100
Immune System II: Immune Responses in Health and Disease (3)
Class Number: 5407
Delivery Method: In Person
Overview
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Course Times + Location:
Jan 5 – Apr 11, 2016: Wed, Fri, 2:30–4:20 p.m.
Burnaby
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Instructor:
Jonathan Choy
jcc54@sfu.ca
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Prerequisites:
MBB 426 or HSCI 426, with a minimum grade of C.
Description
CALENDAR DESCRIPTION:
The immunologic response to bacterial, viral and parasitic infections, immunological diseases, such as autoimmune diseases, immunodeficiency, hypersensitivity reactions (including asthma and allergy) and transplantation-rejection reactions. Immunotherapeutics and vaccine development. Students with credit for HSCI 427 may not repeat this course for further credit.
COURSE DETAILS:
Course Description
The immunological basis of host-pathogen interactions and of immunological disorders such as immunodeficiencies, autoimmunity, hypersensitivity (including allergy and asthma), organ transplant rejection and cancer.
Many diseases are caused by dysregulation of the immune system. This course will examine the immunological mechanisms underlying human immunodeficiencies, HIV infection, asthma and allergy, autoimmunity, and organ transplantation. Immune responses to cancer and cancer immunotherapy will also be discussed.
Lecture Topics
1. Evasion and subversion of host defenses by pathogens
2. Human immunodeficiencies
3. Acquired immunodeficiency
4. Allergy and hypersensitivity
5. Physiological induction and maintenance of tolerance
6. Autoimmunity
7. Transplantation
8. Tumor immunology and immunotherapy
Grading
- 2 non-cumulative exams (30% each) 60%
- 1 in-class presentation with written summary 30%
- Class participation 10%
Materials
REQUIRED READING:
Abul K. Abbas et al. Cellular and Molecular Immunology, 8th Ed. 2015. Elsevier.
ISBN: 978-0-323-22275-4
Original research articles and review articles
Department Undergraduate Notes:
- Students are advised to review the plagiarism tutorial found at
http://www.lib.sfu.ca/help/tutorials/plagiarism-tutorial - For help with writing, learning and study strategies please contact the Student Learning Commons at
http://learningcommons.sfu.ca/ - Students requiring accommodations as a result of a disability, must contact the Centre for Students with Disabilities (778-782-3112 or e-mail: csdo@sfu.ca)
Registrar Notes:
SFU’s Academic Integrity web site http://students.sfu.ca/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating. Check out the site for more information and videos that help explain the issues in plain English.
Each student is responsible for his or her conduct as it affects the University community. Academic dishonesty, in whatever form, is ultimately destructive of the values of the University. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the University. http://www.sfu.ca/policies/gazette/student/s10-01.html
ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS