Summer 2016 - MBB 729 G100
RNA-mediated Gene Regulation (3)
Class Number: 5502
Delivery Method: In Person
RNA plays an important role in gene regulation. This course will explore recent primary literature studying the biochemistry of these processes. Students who have taken MBB 420 or MBB 829 under the same title cannot take this course for further credit.
1. RNA interference in plants and animals.
2. CRISPR bacterial antiviral defense.
3. Transcriptional and translational regulation – riboswitches, tmRNA, IRES elements, 6S RNA, etc.
4. Post-transcriptional processing – editing, capping and splicing. Naturally occurring ribozymes.
- Essay 50%
- Final exam 25%
- Presentation to undergraduates 25%
None. This course is based on primary literature (journal articles). Supplementary material will be made available from selected texts or journal articles.
Bloomfield, Crothers and Tinoco. Nucleic Acids Structures, Properties and Functions, 2000. University Science Books. This text is a great nucleic acid resource.
Graduate Studies Notes:
Important dates and deadlines for graduate students are found here: http://www.sfu.ca/dean-gradstudies/current/important_dates/guidelines.html. The deadline to drop a course with a 100% refund is the end of week 2. The deadline to drop with no notation on your transcript is the end of week 3.