Fall 2017 - MBB 421 D100

Nucleic Acids (3)

Class Number: 6121

Delivery Method: In Person

Overview

  • Course Times + Location:

    Tu, Th 10:30 AM – 12:20 PM
    AQ 5037, Burnaby

  • Instructor:

    Dipankar Sen
    sen@sfu.ca
    1 778 782-4386
  • Prerequisites:

    MBB 331 with a minimum grade of C.

Description

CALENDAR DESCRIPTION:

Recent literature is examined for insights into the structure and properties of DNA and RNA, drawing on a variety of biochemical, chemical and molecular biological perspectives.

COURSE DETAILS:

Lecture Topics:

  1. Sugars, bases, and nucleotides.
  2. DNA structure.
  3. Chromatin
  4. Recombination structures
  5. RNA structure.
  6. RNA - ligand (proteins and drugs) interactions
  7. DNA - ligand (proteins and drugs) interactions
  8. Catalytic RNA
  9. RNA and the origin of life.

Grading

  • 2 exams 95%
  • Class presentation 5%

Materials

RECOMMENDED READING:

G.M. Blackburn, M.J. Gait, David Loakes, David Williams (editors). Nucleic Acids in Chemistry and Biology, 3rd Edition, 2006. Royal Society of Chemistry.
ISBN: 978-0854046546

Department Undergraduate Notes:

  • Students are advised to review the plagiarism tutorial found at
    http://www.lib.sfu.ca/help/tutorials/plagiarism-tutorial
  • For help with writing, learning and study strategies please contact the Student Learning Commons at
    http://learningcommons.sfu.ca/
  • Students requiring accommodations as a result of a disability, must contact the Centre for Students with Disabilities (778-782-3112 or e-mail:  csdo@sfu.ca)

Registrar Notes:

SFU’s Academic Integrity web site http://students.sfu.ca/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating.  Check out the site for more information and videos that help explain the issues in plain English.

Each student is responsible for his or her conduct as it affects the University community.  Academic dishonesty, in whatever form, is ultimately destructive of the values of the University. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the University. http://www.sfu.ca/policies/gazette/student/s10-01.html

ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS