Spring 2017 - HSCI 427 D100

Immune System II: Immune Responses in Health and Disease (3)

Class Number: 4343

Delivery Method: In Person

Overview

  • Course Times + Location:

    Jan 4 – Apr 7, 2017: Wed, Fri, 2:30–4:20 p.m.
    Burnaby

  • Prerequisites:

    HSCI 426 or MBB 426 or permission of the instructor.

Description

CALENDAR DESCRIPTION:

The immunologic response to bacterial, viral and parasitic infections, immunological diseases, such as autoimmune diseases, immunodeficiency, hypersensitivity reactions (including asthma and allergy) and transplantation-rejection reactions. Immunotherapeutics and vaccine development. HSCI 427 is identical to MBB 427 and HSCI 425 and students may not take this course for further credit.

COURSE DETAILS:

Course Description
The immunological basis of host-pathogen interactions and of immunological disorders such as immunodeficiencies, autoimmunity, hypersensitivity (including allergy and asthma), organ transplant rejection and cancer.  

Many diseases are caused by dysregulation of the immune system. This course will examine the immunological mechanisms underlying human immunodeficiencies, HIV infection, asthma and allergy, autoimmunity, and organ transplantation. Immune responses to cancer and cancer immunotherapy will also be discussed.

Lecture Topics
1.     Evasion and subversion of host defenses by pathogens
2.     Human immunodeficiencies
3.     Acquired immunodeficiency
4.     Allergy and hypersensitivity
5.     Physiological induction and maintenance of tolerance
6.     Autoimmunity
7.     Transplantation
8.     Tumor immunology and immunotherapy

Grading

  • 2 non-cumulative exams (30% each) 60%
  • 1 in-class presentation with written summary 30%
  • Class participation 10%

NOTES:

Students who have taken MBB 427 or HSCI 427 may not receive credit for MBB 727 and vice versa.

REQUIREMENTS:

MBB426 or HSCI 426. HSCI 427 is identical to MBB 427 and students cannot receive credit for both courses.

Materials

REQUIRED READING:

Kenneth Murphy and Casey Weaver. Janeway's Immunobiology, 9th Ed. 2017. Garland Science.
ISBN: 978-0-8153-4505-3

Original research articles and review articles

Registrar Notes:

SFU’s Academic Integrity web site http://students.sfu.ca/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating.  Check out the site for more information and videos that help explain the issues in plain English.

Each student is responsible for his or her conduct as it affects the University community.  Academic dishonesty, in whatever form, is ultimately destructive of the values of the University. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the University. http://www.sfu.ca/policies/gazette/student/s10-01.html

ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS