Spring 2018 - MBB 321 D100

Intermediary Metabolism (3)

Class Number: 3644

Delivery Method: In Person


  • Course Times + Location:

    Mo, We 11:30 AM – 12:20 PM
    AQ 3182, Burnaby

    Fr 11:30 AM – 12:20 PM
    SSCB 9200, Burnaby

  • Exam Times + Location:

    Apr 16, 2018
    3:30 PM – 6:30 PM
    SSCB 9200, Burnaby

  • Prerequisites:

    MBB 231, with a minimum grade of C.



The enzymes and intermediates of major catabolic and anabolic pathways. Their regulation and integration in health and disease states.


Lecture Topics:

  1. Review of bioenergetics, reaction mechanisms
  2. Catalysis, enzyme kinetics
  3. Carbohydrates: structure, glycogen metabolism
  4. Carbohydrates: glycolysis, citric acid cycle
  5. Carbohydrates: gluconeogenesis, pentose phosphate pathway
  6. Electron transport, oxidative phosphorylation
  7. Mitochondrial transport systems, lipid structure
  8. Lipids: beta oxidation, fatty acid biosynthesis
  9. Lipids: phospholipid biosynthesis, steroid metabolism
  10. Lipids: eicosanoid metabolism, amino acid metabolism
  11. Amino acids: urea cycle, nitrogen cycle
  12. Nucleotide biosynthesis and catabolism
  13. Metabolic regulation


  • Midterms 3 or 4 70%
  • Final Exam 30%



Cox and Nelson, Lehninger Principles of Biochemistry, 7th edition, 2017. W.H. Freeman & Company.

Note:  Students that do not already own the 7th edition from a previous course may use the 6th edition of the same textbook (2012). An abridged version of the 7th edition containing relevant chapters will be available from the SFU Bookstore.

Department Undergraduate Notes:

  • Students are advised to review the plagiarism tutorial found at
  • For help with writing, learning and study strategies please contact the Student Learning Commons at
  • Students requiring accommodations as a result of a disability, must contact the Centre for Students with Disabilities (778-782-3112 or e-mail:  csdo@sfu.ca)

Registrar Notes:

SFU’s Academic Integrity web site http://students.sfu.ca/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating.  Check out the site for more information and videos that help explain the issues in plain English.

Each student is responsible for his or her conduct as it affects the University community.  Academic dishonesty, in whatever form, is ultimately destructive of the values of the University. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the University. http://www.sfu.ca/policies/gazette/student/s10-01.html