Simon Fraser University
Engaging the World

Course Outlines

Summer 2018 - MBB 729 G100

RNA-mediated Gene Regulation (3)

Class Number: 6070

Delivery Method: In Person

Overview

  • Course Times + Location:

    May 7 – Aug 3, 2018: Wed, Fri, 8:30–10:20 a.m.
    Burnaby

  • Exam Times + Location:

    Aug 13, 2018
    Mon, 12:00–3:00 p.m.
    Burnaby

Description

CALENDAR DESCRIPTION:

RNA plays an important role in gene regulation. This course will explore recent primary literature studying the biochemistry of these processes. Students who have taken MBB 420 or MBB 829 under the same title cannot take this course for further credit.

COURSE DETAILS:

Topics

1.  RNA interference in plants and animals.
2.  CRISPR bacterial antiviral defense.
3.  Transcriptional and translational regulation – riboswitches, tmRNA, IRES elements, 6S RNA, etc.
4.  Post-transcriptional processing – editing, capping and splicing. Naturally occurring ribozymes.

Grading

  • Essay 50%
  • Class participation 25%
  • Presentation to undergraduates 25%

Materials

REQUIRED READING:

None.  This course is based on primary literature (journal articles). Supplementary material will be made available from selected texts or journal articles.

RECOMMENDED READING:

Bloomfield, Crothers and Tinoco. Nucleic Acids Structures, Properties and Functions, 2000. University Science Books.  This text is a great nucleic acid resource.
ISBN: 0-935702-49-0

Graduate Studies Notes:

Important dates and deadlines for graduate students are found here: http://www.sfu.ca/dean-gradstudies/current/important_dates/guidelines.html. The deadline to drop a course with a 100% refund is the end of week 2. The deadline to drop with no notation on your transcript is the end of week 3.

Registrar Notes:

SFU’s Academic Integrity web site http://students.sfu.ca/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating.  Check out the site for more information and videos that help explain the issues in plain English.

Each student is responsible for his or her conduct as it affects the University community.  Academic dishonesty, in whatever form, is ultimately destructive of the values of the University. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the University. http://www.sfu.ca/policies/gazette/student/s10-01.html

ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS