Spring 2019 - MBB 462 D100
Human Genomics (3)
Class Number: 3621
Delivery Method: In Person
Overview
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Course Times + Location:
Jan 3 – Apr 8, 2019: Tue, Thu, 2:30–4:20 p.m.
Burnaby
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Instructor:
Robert Holt
rah6@sfu.ca
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Prerequisites:
MBB 331 and MBB 342, with a minimum grade of C.
Description
CALENDAR DESCRIPTION:
The organization of the human genome and the role of genomic variation in health and disease. Genomics and personalized medicine; intellectual property and privacy issues. Students with credit for MBB 440 with this same course title may not complete this course for further credit.
COURSE DETAILS:
Description/topics: This course will explore the organization of the human genome and the role of genome variation in health and disease. A broad range of topics will be covered including, for example, human genetic history, immunogenomics, pharmacogenomics, neurogenomics, genomics technologies and genetic engineering. We will also cover the business of genomics, including direct-to-consumer genetic testing, intellectual property issues and the biotechnology industry.
In this course considerable emphasis will be placed on participation and critical thinking. Instruction will include lecture material and assigned reading from selected textbook chapters, review articles, the press, and various online sources. There will be in-depth consideration of selected seminal papers, and papers describing recent advances in topics relevant to human genomics. Depending on the availability of 3rd party genotyping services, students will explore aspects of their personal genome as part of this course (participation will be optional and extra costs may apply).
Grading
- There will be two exams, one for the first half of the course and one for the second half of the course. Exams will cover lecture material and assigned reading. 60%
- There will be two take-home assignments 25%
- Participation, including contributing to the presentation of a critical analysis of a research paper 15%
Materials
RECOMMENDED READING:
Genomes 4, 4th Edition. 2017. By Terry A. Brown
Exploring Personal Genomics. 2013. Dudley & Karczewski
Department Undergraduate Notes:
- Students are advised to review the plagiarism tutorial found at
http://www.lib.sfu.ca/help/tutorials/plagiarism-tutorial - For help with writing, learning and study strategies please contact the Student Learning Commons at
http://learningcommons.sfu.ca/ - Students requiring accommodations as a result of a disability, must contact the Centre for Students with Disabilities (778-782-3112 or e-mail: csdo@sfu.ca)
Registrar Notes:
SFU’s Academic Integrity web site http://www.sfu.ca/students/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating. Check out the site for more information and videos that help explain the issues in plain English.
Each student is responsible for his or her conduct as it affects the University community. Academic dishonesty, in whatever form, is ultimately destructive of the values of the University. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the University. http://www.sfu.ca/policies/gazette/student/s10-01.html
ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS