Fall 2020 - MBB 331 D100

Molecular Biology (4)

Class Number: 2966

Delivery Method: In Person

Overview

  • Course Times + Location:

    Tu, Th 10:30 AM – 12:20 PM
    REMOTE LEARNING, Burnaby

  • Instructor:

    Chris Beh
  • Prerequisites:

    MBB 231, and BISC 202, with a minimum grade of C.

Description

CALENDAR DESCRIPTION:

The study of DNA and RNA in relation to gene structure and expression: DNA replication and the regulation of gene expression in bacteria and higher organisms. Introduction to recombinant DNA and cloning theory; natural vector structures and recombinant vector construction.

COURSE DETAILS:

Molecular biology has transformed the life sciences over the last half century and continues to advance rapidly, bringing with it profound implications for the future of biology, medicine, and agriculture. Our look at molecular biology will extend from its early history and basic principles through to recent developments and future directions. In our consideration of the current status of molecular biology, the emphasis will be placed on examining recent findings from primary scientific journals. Textbooks can only supply information that is current up to several years ago, and we must consider the primary literature to learn about recent advances. The tutorial project is designed to familiarize you with reading and evaluating research papers. You will choose a recent paper from any area of modern molecular biology and do a short oral presentation together with a one page summary of the paper. Oral presentations will be followed by a short question and discussion period.

Lecture Topics:

  • Introduction: Overview of molecular biology and its history
  • Structure and function of nucleic acids
  • Recombinant DNA methods
  • Replication, recombination and repair
  • Prokaryotic gene organization, expression and regulation
  • Bacterial viruses
  • Eukaryotic gene organization, expression and regulation

Grading

  • 3 midterms (20% each) 60%
  • Online weekly quizzes 10%
  • Tutorials (20% presentation + 10% participation) 30%

NOTES:

  • Lectures:  asynchronous (pre-recorded, available online) and synchronous (students are offered scheduled times to question remotely)
  • Tutorial:  synchronous (students are expected to attend scheduled tutorials remotely)
  • Assessments:  synchronous (tutorial presentations, quizzes, 3 midterm exams)
  • Remote invigilation:  possibly

Materials

MATERIALS + SUPPLIES:

  • Access to high-speed internet
  • Computer with Webcam (headphones and microphone if not built in)

REQUIRED READING:

Molecular Biology: Principles and Practice, 2nd edition, by Michael M. Cox, Jennifer A. Doudna, Michael O'Donnell, W.H. Freeman & Company, 2015.  eText also available.
ISBN: 9781464126147

Department Undergraduate Notes:


  • For help with writing, learning and study strategies please contact the Student Learning Commons at
    http://learningcommons.sfu.ca/
  • Students requiring accommodations as a result of a disability, must contact the Centre for Accessible Learning (778-782-3112 or e-mail:  caladmin@sfu.ca)

Registrar Notes:

ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS

SFU’s Academic Integrity web site http://www.sfu.ca/students/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating.  Check out the site for more information and videos that help explain the issues in plain English.

Each student is responsible for his or her conduct as it affects the University community.  Academic dishonesty, in whatever form, is ultimately destructive of the values of the University. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the University. http://www.sfu.ca/policies/gazette/student/s10-01.html

TEACHING AT SFU IN FALL 2020

Teaching at SFU in fall 2020 will be conducted primarily through remote methods. There will be in-person course components in a few exceptional cases where this is fundamental to the educational goals of the course. Such course components will be clearly identified at registration, as will course components that will be “live” (synchronous) vs. at your own pace (asynchronous). Enrollment acknowledges that remote study may entail different modes of learning, interaction with your instructor, and ways of getting feedback on your work than may be the case for in-person classes. To ensure you can access all course materials, we recommend you have access to a computer with a microphone and camera, and the internet. In some cases your instructor may use Zoom or other means requiring a camera and microphone to invigilate exams. If proctoring software will be used, this will be confirmed in the first week of class.

Students with hidden or visible disabilities who believe they may need class or exam accommodations, including in the current context of remote learning, are encouraged to register with the SFU Centre for Accessible Learning (caladmin@sfu.ca or 778-782-3112).