Spring 2020 - BISC 302W D100
Genetic Analysis (3)
Class Number: 2552
Delivery Method: In Person
Course Times + Location:
Tu 10:30 AM – 11:20 AM
BLU 10011, Burnaby
Th 10:30 AM – 11:20 AM
AQ 3003, Burnaby
Exam Times + Location:
Apr 18, 2020
12:00 PM – 3:00 PM
AQ 3159, Burnaby
1 778 782-5611
Prerequisites:BISC 202 with a grade of C- or better.
Discussion and manipulations of some of the organisms and techniques applicable to genetic analysis. Students are required to come into the lab on average of two hours per week in addition to the four hour scheduled lab each week for project work. Students with credit for BISC 302 may not take this course for further credit. Writing.
Lecture/Laboratory course using model eukaryotes. We will assume you understand the basics of genes, gene mapping, recombination and segregation from Bisc 202. The laboratory will include experiments involving several model organisms, including corn, Drosophila, Sordaria (a filamentous fungus), and case studies involving human genetics scenarios. We are piloting a new genotyping project using dog DNA. The work for the project will be done in groups of 3 to 5.
The project may require some time in the lab outside of regular lab times.
Experiments will include gene mapping, using standard genetic crosses, as well as tetrad analysis. Other labs will cover extraction of DNA, and PCR (polymerase chain reaction) amplification of selected DNA regions. Most labs will involve problem solving and case studies.
The lecture topics will include a review of standard genetic mapping, advanced mapping and tetrad analysis, mechanisms of recombination, gene conversion, epigenetics, transposable elements, sex-linkage (including the origin and evolution of sex chromosomes), and forward and reverse genetic approaches. The final lecture(s) may cover student-selected topics. Basic lectures recorded in advance, come to class prepared to answer questions and solve problems.
This is a writing intensive course, which means that 50% of the grade will be based on written work, both formal writing and in-lab writing.
- Laboratory worksheets and in-lab writing 25%
- Lab quizzes 10%
- Clickers 10%
- Final Exam 10%
- Midterm Exam 10%
- Research proposal for genetic screen 5%
- Short lab report, fly eye colour 10%
- Dog genotyping report 20%
This is a rough guideline that could change a little
MATERIALS + SUPPLIES:
Required: iClickers will be used in class
There is no Required Textbook for this course
Whatever genetics text you already have is fine (material is provided as review papers and recorded introductions to the topics we will cover)
SFU’s Academic Integrity web site http://www.sfu.ca/students/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating. Check out the site for more information and videos that help explain the issues in plain English.
Each student is responsible for his or her conduct as it affects the University community. Academic dishonesty, in whatever form, is ultimately destructive of the values of the University. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the University. http://www.sfu.ca/policies/gazette/student/s10-01.html
ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS