Fall 2021 - HSCI 323 D100

Principles of Pharmacology and Toxicology (3)

Class Number: 2129

Delivery Method: In Person


  • Course Times + Location:

    Th 8:30 AM – 11:20 AM
    BLU 9011, Burnaby

  • Instructor:

    Timothy Beischlag
    1 778 782-3071
  • Prerequisites:

    MBB 231, CHEM 282, both with a minimum grade of C-.



Biological, molecular and biochemical actions of drugs and toxicants. Genetic and environmental risk determinants. Understanding the broad spectrum of toxicological problems encountered in clinical practice, drug development and regulation, and medical research.


This course will provide students with an introduction to pharmacological and toxicological principles, and in particular pharmacokinetics and pharmacodynamics. In addition, students will be provided with an overview of mechanisms of drug/toxicant action on various systems, and receptors, including signal transduction pathways. Finally, students will be introduced to the topics of pharmaco-/toxico-genetics and genomics. This course is designed to prepare undergraduates who have an interest in medicine and human health services to pursue careers in these disciplines. In addition, this course will serve as the cornerstone of the Environmental and Occupational Health Bachelor of Science stream and support the Life Course in Human Health stream in the Faculty of Health Sciences.


The objectives of this course are to provide students with a firm and demonstrable understanding of the basic principles of pharmacology and toxicology. By the end of the course students will be able to:
1. Explain relevant principles of drug action such as absorption, distribution, metabolism, bio-activation, and the laws of mass action as they relate to the physiology of drug and toxicant action in the body.
2. The students should begin to be able to apply or relate this knowledge to practical pharmacological/toxicological problems commonly associated with human populations and those confronted in a basic laboratory situation. This should be evident by the student’s ability to extend theory to practice and/or provide relevant examples from the literature.
3. Students should be able to identify what parameters, with regard to dose/exposure, peak plasma concentration, etc., are physiologically relevant.



Details Regarding Course Grades and Evaluation. There will be three multiple choice and short answer format mid-term exams, each will represent 33.33% of the final grade. Exams will be non-cumulative, i.e. they will only cover the material for that specific third of the course. The grade scale will follow the standard Canadian grading scale (i.e. ≥93% = A+, 85-89% = A, 80-84% = A-, etc.). This scale is available in the FHS undergraduate education office.



Rang & Dale's Pharmacology , 9th Edition

Registrar Notes:


SFU’s Academic Integrity web site http://www.sfu.ca/students/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating.  Check out the site for more information and videos that help explain the issues in plain English.

Each student is responsible for his or her conduct as it affects the University community.  Academic dishonesty, in whatever form, is ultimately destructive of the values of the University. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the University. http://www.sfu.ca/policies/gazette/student/s10-01.html


Teaching at SFU in fall 2021 will involve primarily in-person instruction, with approximately 70 to 80 per cent of classes in person/on campus, with safety plans in place.  Whether your course will be in-person or through remote methods will be clearly identified in the schedule of classes.  You will also know at enrollment whether remote course components will be “live” (synchronous) or at your own pace (asynchronous).

Enrolling in a course acknowledges that you are able to attend in whatever format is required.  You should not enroll in a course that is in-person if you are not able to return to campus, and should be aware that remote study may entail different modes of learning, interaction with your instructor, and ways of getting feedback on your work than may be the case for in-person classes.

Students with hidden or visible disabilities who may need class or exam accommodations, including in the context of remote learning, are advised to register with the SFU Centre for Accessible Learning (caladmin@sfu.ca or 778-782-3112) as early as possible in order to prepare for the fall 2021 term.