Summer 2022 - MBB 402 D100
Developmental Biology of Cell Signalling (3)
Class Number: 2625
Delivery Method: In Person
Course Times + Location:
We, Fr 2:30 PM – 4:20 PM
AQ 3149, Burnaby
1 778 782-5642
1 778 782-3541
Prerequisites:MBB 331 or BISC 302W with a minimum grade of C.
Aspects of developmental biology in the context of signal transduction pathways. The diverse mechanisms used in cell signalling and how the various approaches to the study of signal transduction in organismal development complement each other will be examined with an emphasis on current literature.
In this lecture/seminar course, we will examine select aspects of developmental and cellular biology with a focus on signal transduction. Signaling pathways control a wide range of cellular processes and the characterization of these pathways is having a major impact on cell biology, developmental biology and medicine. In this course, we shall be examining the current literature in this rapidly developing field. We will look at how a combination of biochemistry, cell biology and genetics is being used to investigate the diverse mechanisms used in cell signaling, and examine how the various approaches to studying signal transduction compliment each other.
Specific Topics will include:
- Introduction: mechanisms of signal transduction, approaches available for studying signal transduction
- Signaling pathways involving small GTPase and trimeric G proteins
- Signaling by proteolytic cleavages
- Wnt and Hedgehog signaling pathways
- Regulation of signaling by Kinases and Phosphatases
- Other topics as time permits
- Midterm Exam 20%
- Oral Presentation 25%
- Class Participation 15%
- Final Term Paper 40%
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TEACHING AT SFU IN SUMMER 2022
Teaching at SFU in summer 2022 will involve primarily in-person instruction. Some courses may be offered through alternative methods (remote, online, blended), and if so, this will be clearly identified in the schedule of classes.
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Students with hidden or visible disabilities who may need class or exam accommodations, including in the context of remote learning, are advised to register with the SFU Centre for Accessible Learning (firstname.lastname@example.org or 778-782-3112) as early as possible in order to prepare for the summer 2022 term.