Spring 2023 - MBB 669 G100
Special Topics in Genomics (3)
Class Number: 5572
Delivery Method: In Person
Consideration of recent research literature on contemporary topics in genomics.
An examination of the genomic changes that accrue during the formation and treatment of human cancer.
The course will examine the role that genetic mutations play in the development of human cancer and tumour formation. We will study the spectrum of different types of genetic alterations that accrue and their distribution across different cancer types. We will study the technologies that allow these changes to be detected and how they are interpreted clinically. Students with credit for MBB 460 under the title "Cancer Genomics" may not take this course for further credit.
- Cancer sequencing
- Tumour heterogeneity
- DNA repair
- Hereditary cancer
- Treatment resistance
- Neo-antigens and immunotherapy
- Cancer epigenomics
- Gene expression and alternative splicing in cancer
- Personalized oncogenomics
- Mutational signatures
- In-class presentation 30%
- Writing assignment 50%
- Class participation 20%
REQUIRED READING NOTES:
Your personalized Course Material list, including digital and physical textbooks, are available through the SFU Bookstore website by simply entering your Computing ID at: shop.sfu.ca/course-materials/my-personalized-course-materials.
Graduate Studies Notes:
Important dates and deadlines for graduate students are found here: http://www.sfu.ca/dean-gradstudies/current/important_dates/guidelines.html. The deadline to drop a course with a 100% refund is the end of week 2. The deadline to drop with no notation on your transcript is the end of week 3.
ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS
SFU’s Academic Integrity website http://www.sfu.ca/students/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating. Check out the site for more information and videos that help explain the issues in plain English.
Each student is responsible for his or her conduct as it affects the university community. Academic dishonesty, in whatever form, is ultimately destructive of the values of the university. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the university. http://www.sfu.ca/policies/gazette/student/s10-01.html