Spring 2023 - MBB 738 G100

Human Molecular Genetics (3)

Class Number: 3881

Delivery Method: In Person

Overview

  • Course Times + Location:

    Jan 4 – Apr 11, 2023: Tue, Thu, 10:30 a.m.–12:20 p.m.
    Burnaby

  • Prerequisites:

    MBB 331 (or BISC 331) or equivalent.

Description

CALENDAR DESCRIPTION:

The course will consider recent advances in human molecular genetics. Topics will include genome analysis, genetic testing, and studies of genetic disorders.

COURSE DETAILS:

This course will focus on recent advances in human molecular genetics.  This lecture and seminar course will cover the topics listed below and will integrate primary research papers into the topics. 4 lecture hours/week.

Lecture Topics:
1. Human genetic disease inheritance
2. Molecular analysis of single gene disorders
3. Genetic analysis of complex disease
4. Gene therapy
5. Gene testing
6. Cloning and stem cells
7. Animal models of human diseases
8. Ethical considerations of human genetics
9. Genetically modified organisms and food

Grading

  • Three non-cumulative exams (25% each) 75%
  • Short science communication paper 10%
  • In-class presentation 15%

Materials

RECOMMENDED READING:

Human Molecular Genetics by Strachan and Read, and Genetics and Genomics in Medicine by Strachan et al. are excellent recommended references for the material. We will also be reading papers from the primary literature.

REQUIRED READING NOTES:

Your personalized Course Material list, including digital and physical textbooks, are available through the SFU Bookstore website by simply entering your Computing ID at: shop.sfu.ca/course-materials/my-personalized-course-materials.

Graduate Studies Notes:

Important dates and deadlines for graduate students are found here: http://www.sfu.ca/dean-gradstudies/current/important_dates/guidelines.html. The deadline to drop a course with a 100% refund is the end of week 2. The deadline to drop with no notation on your transcript is the end of week 3.

Registrar Notes:

ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS

SFU’s Academic Integrity website http://www.sfu.ca/students/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating. Check out the site for more information and videos that help explain the issues in plain English.

Each student is responsible for his or her conduct as it affects the university community. Academic dishonesty, in whatever form, is ultimately destructive of the values of the university. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the university. http://www.sfu.ca/policies/gazette/student/s10-01.html