Simon Fraser University
Engaging the World

Course Outlines

Spring 2025 - HSCI 321 D100

Human Pathophysiology (3)

Class Number: 3492

Delivery Method: In Person

Overview

  • Course Times + Location:

    Jan 6 – Apr 9, 2025: Mon, 2:30–5:20 p.m.
    Burnaby

  • Exam Times + Location:

    Apr 24, 2025
    Thu, 7:00–10:00 p.m.
    Burnaby

  • Prerequisites:

    MBB 231 with a minimum grade of C- or permission of the instructor.

Description

CALENDAR DESCRIPTION:

Molecular, cellular and systemic approach to examine topics in human pathophysiology.

COURSE DETAILS:

PREREQUISITES: MBB 231

This course will introduce topics in the pathophysiological mechanisms of disease. To provide a foundation to explore human pathophysiology, this course will build on topics of cellular and molecular biology to understand human physiology at the systemic and integrative level. Functional human anatomy will be described when necessary to understand essential concepts. This course is designed to prepare undergraduates who have an interest in biomedical research, medicine, and human health services to pursue
careers in these disciplines. In addition, this course will support the Bachelor of Science in the Faculty of Health Sciences and may be of interest to students in other faculties including Science (BISC, BPK, MBB).

COURSE-LEVEL EDUCATIONAL GOALS:

  • Upon the completion of this course students should be familiar with fundamental principles of human physiology
  • Upon the completion of this course, students to be able to explain several biological mechanisms governing disease pathogenesis in humans.
  • Upon the completion of this course, students should be able to demonstrate and exemplify differences arising from disease states, including skills in diagnosing case studies and recognizing disease risk factors and outcomes.
  • Upon the completion of this course, students should have the background to succeed in more intensive and comprehensive courses covering anatomy, physiology, pathology, and allied disciplines.

TOPICS:
Each section/topic will include an examination of molecular to systems-level biology, across
health and disease, of different tissue and organ systems:
  • Cardiovascular system
  • Respiratory system
  • Gastrointestinal system
  • Nervous system
  • Endocrine system
Given the time constraints of this course, we cannot cover all systems and even all physiology/pathology relevant to the above systems. The goal is provide enough working knowledge to see how systems connect and work as a whole and with this starting further understanding can be achieved independently and in future contexts.

Grading

  • Case Studies (5 x 6% each) 30%
  • Exams (x 3) 60%
  • Questions, answers & discussion 10%

Materials

RECOMMENDED READING:

RECOMMENDED TEXTS:
Guyton and Hall. Textbook of Medical Physiology. 11th,12th,13th or 14th Ed. Elsevier
Robbins & Cotran. Pathologic Basis of Disease. 7th, 8th, 9th or 10th Ed. Elsevier

REQUIRED READING NOTES:

Your personalized Course Material list, including digital and physical textbooks, are available through the SFU Bookstore website by simply entering your Computing ID at: shop.sfu.ca/course-materials/my-personalized-course-materials.

Registrar Notes:

ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS

SFU’s Academic Integrity website http://www.sfu.ca/students/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating. Check out the site for more information and videos that help explain the issues in plain English.

Each student is responsible for his or her conduct as it affects the university community. Academic dishonesty, in whatever form, is ultimately destructive of the values of the university. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the university. http://www.sfu.ca/policies/gazette/student/s10-01.html

RELIGIOUS ACCOMMODATION

Students with a faith background who may need accommodations during the term are encouraged to assess their needs as soon as possible and review the Multifaith religious accommodations website. The page outlines ways they begin working toward an accommodation and ensure solutions can be reached in a timely fashion.