Summer 2025 - MBB 443 D100
Protein Biogenesis and Degradation (3)
Class Number: 4208
Delivery Method: In Person
Overview
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Course Times + Location:
May 12 – Aug 8, 2025: Tue, Thu, 8:30–10:20 a.m.
Burnaby -
Exam Times + Location:
Aug 21, 2025
Thu, 7:00–10:00 p.m.
Burnaby
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Instructor:
Michel Leroux
leroux@sfu.ca
1 778 782-5642
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Prerequisites:
MBB 321 and MBB 322, with a minimum grade of C.
Description
CALENDAR DESCRIPTION:
A consideration of protein biogenesis (folding, assembly, and targeting to cellular compartments), modification, and degradation, and their roles in protein and cellular function.
COURSE DETAILS:
Course Description The central dogma of molecular biology (DNA --› RNA --› PROTEIN) underscores two fundamental biological processes, transcription and translation, that are essential to life. Protein biogenesis (folding, assembly, targeting to the proper cellular compartment), and protein degradation represent two other equally important cellular activities. The emphasis in this course will be to review the literature on protein biogenesis and degradation, and explore the new and exciting developments that are just starting to uncover how mechanistically complex these processes are.
Grading
- Midterm I 25%
- Oral Presentation 15%
- Term Paper 20%
- Midterm II 40%
Materials
MATERIALS + SUPPLIES:
None.
REQUIRED READING:
None.
RECOMMENDED READING:
None.
REQUIRED READING NOTES:
Your personalized Course Material list, including digital and physical textbooks, are available through the SFU Bookstore website by simply entering your Computing ID at: shop.sfu.ca/course-materials/my-personalized-course-materials.
Department Undergraduate Notes:
- For help with writing, learning and study strategies please contact the Student Learning Commons at
http://learningcommons.sfu.ca/ - Students requiring accommodations as a result of a disability, must contact the Centre for Accessible Learning (778-782-3112 or e-mail: caladmin@sfu.ca)
Registrar Notes:
ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS
At SFU, you are expected to act honestly and responsibly in all your academic work. Cheating, plagiarism, or any other form of academic dishonesty harms your own learning, undermines the efforts of your classmates who pursue their studies honestly, and goes against the core values of the university.
To learn more about the academic disciplinary process and relevant academic supports, visit:
- SFU’s Academic Integrity Policy: S10-01 Policy
- SFU’s Academic Integrity website, which includes helpful videos and tips in plain language: Academic Integrity at SFU
RELIGIOUS ACCOMMODATION
Students with a faith background who may need accommodations during the term are encouraged to assess their needs as soon as possible and review the Multifaith religious accommodations website. The page outlines ways they begin working toward an accommodation and ensure solutions can be reached in a timely fashion.