Simon Fraser University
Engaging the World

Course Outlines

Spring 2026 - BISC 302W D100

Genetic Analysis (4)

Class Number: 2363

Delivery Method: In Person

Overview

  • Course Times + Location:

    Jan 5 – Apr 10, 2026: Tue, 9:30–10:20 a.m.
    Burnaby

    Jan 5 – Apr 10, 2026: Thu, 9:30–10:20 a.m.
    Burnaby

  • Prerequisites:

    BISC 202 and MBB 222, both with a minimum grade of C-.

Description

CALENDAR DESCRIPTION:

Students analyze different types of genetic data (e.g., genetic crosses, chromosome rearrangements, STR, RFLP) and use lab techniques (e.g., PCR, restriction digest, and gel electrophoresis) to solve case studies and genetics problems. Writing.

COURSE DETAILS:

Lecture/Laboratory course using model eukaryotes. We will assume you understand the basics of genes, gene mapping, recombination and segregation from BISC 202. The laboratory will include experiments involving several model organisms, including corn, Drosophila (fruit flies), Sordaria (a filamentous fungus), and case studies involving human genetics scenarios. We are also running a genotyping project using dog DNA. The work in most of the labs will be done in groups of 3 to 5.  Some will be done individually also.
 
The experiments may require some time in the lab outside of regular lab times. This time is to be shared among the team members. Each semester may differ slightly.
 
Experiments will include gene mapping, using standard genetic crosses, as well as tetrad analysis. Other labs will cover extraction of DNA, and PCR amplification of selected DNA regions. Many labs will involve problem solving and case studies. 
 
The lecture topics will include a review of standard genetic mapping, advanced mapping and tetrad analysis, mechanisms of recombination, epigenetics, transposable elements, sex-linkage (possibly including the origin and evolution of sex chromosomes), and forward and reverse genetic approaches. The final lecture(s) may cover student-selected topics.

Grading

  • Laboratory quizzes, worksheets, and in-lab writing 25%
  • Research Proposal for Genetic Screen (this may be altered to two smaller assignments, 5% each) 10%
  • Short Lab Report, Fly Eye Colour 15%
  • Dog Genotyping Report 20%
  • Final Exam 20%
  • In-lecture iClicker questions 10%

NOTES:

This grading scheme is subject to change.

This is a writing intensive course, which means that 50% of the grade will be based on your own written work, both formal writing and in-lab writing.

Materials

REQUIRED READING:

There is no required text. Any introductory genetics text can be used as a reference. iClickers will be used in most of the lectures.

REQUIRED READING NOTES:

Your personalized Course Material list, including digital and physical textbooks, are available through the SFU Bookstore website by simply entering your Computing ID at: shop.sfu.ca/course-materials/my-personalized-course-materials.

Registrar Notes:

ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS

At SFU, you are expected to act honestly and responsibly in all your academic work. Cheating, plagiarism, or any other form of academic dishonesty harms your own learning, undermines the efforts of your classmates who pursue their studies honestly, and goes against the core values of the university.

To learn more about the academic disciplinary process and relevant academic supports, visit: 


RELIGIOUS ACCOMMODATION

Students with a faith background who may need accommodations during the term are encouraged to assess their needs as soon as possible and review the Multifaith religious accommodations website. The page outlines ways they begin working toward an accommodation and ensure solutions can be reached in a timely fashion.