Clinical Trial for Treatment of Migraine Headaches              1

                               The FREQ Procedure

                  Summary Statistics for Treatment by Improve
                             Controlling for Gender

          Cochran-Mantel-Haenszel Statistics (Based on Table Scores)
 
        Statistic    Alternative Hypothesis    DF       Value      Prob
        ---------------------------------------------------------------
            1        Nonzero Correlation        1      8.3052    0.0040
            2        Row Mean Scores Differ     1      8.3052    0.0040
            3        General Association        1      8.3052    0.0040


               Estimates of the Common Relative Risk (Row1/Row2)
 
   Type of Study     Method                  Value     95% Confidence Limits
   -------------------------------------------------------------------------
   Case-Control      Mantel-Haenszel        3.3132       1.4456       7.5934
     (Odds Ratio)    Logit                  3.2941       1.4182       7.6515

   Cohort            Mantel-Haenszel        2.1636       1.2336       3.7948
     (Col1 Risk)     Logit                  2.1059       1.1951       3.7108

   Cohort            Mantel-Haenszel        0.6420       0.4705       0.8761
     (Col2 Risk)     Logit                  0.6613       0.4852       0.9013


                              Breslow-Day Test for
                         Homogeneity of the Odds Ratios
                         ------------------------------
                         Chi-Square              1.4929
                         DF                           1
                         Pr > ChiSq              0.2218


                            Total Sample Size = 106