Clinical Trial for Treatment of Pain                     1

                               The FREQ Procedure

                            Table of Dose by Adverse

                      Dose      Adverse

                      Frequency|
                      Percent  |
                      Row Pct  |
                      Col Pct  |No      |Yes     |  Total
                      ---------+--------+--------+
                             0 |     26 |      6 |     32
                               |  16.15 |   3.73 |  19.88
                               |  81.25 |  18.75 |
                               |  25.49 |  10.17 |
                      ---------+--------+--------+
                             1 |     26 |      7 |     33
                               |  16.15 |   4.35 |  20.50
                               |  78.79 |  21.21 |
                               |  25.49 |  11.86 |
                      ---------+--------+--------+
                             2 |     23 |      9 |     32
                               |  14.29 |   5.59 |  19.88
                               |  71.88 |  28.13 |
                               |  22.55 |  15.25 |
                      ---------+--------+--------+
                             3 |     18 |     14 |     32
                               |  11.18 |   8.70 |  19.88
                               |  56.25 |  43.75 |
                               |  17.65 |  23.73 |
                      ---------+--------+--------+
                             4 |      9 |     23 |     32
                               |   5.59 |  14.29 |  19.88
                               |  28.13 |  71.88 |
                               |   8.82 |  38.98 |
                      ---------+--------+--------+
                      Total         102       59      161
                                  63.35    36.65   100.00


                    Statistics for Table of Dose by Adverse

                                                                     95%
  Statistic                              Value       ASE     Confidence Limits
  ----------------------------------------------------------------------------
  Gamma                                 0.5313    0.0935     0.3480     0.7146
  Kendall's Tau-b                       0.3373    0.0642     0.2114     0.4631
  Stuart's Tau-c                        0.4111    0.0798     0.2547     0.5675

  Somers' D C|R                         0.2569    0.0499     0.1592     0.3547
  Somers' D R|C                         0.4427    0.0837     0.2786     0.6068

  Pearson Correlation                   0.3776    0.0714     0.2378     0.5175
  Spearman Correlation                  0.3771    0.0718     0.2363     0.5178

  Lambda Asymmetric C|R                 0.2373    0.0837     0.0732     0.4014
  Lambda Asymmetric R|C                 0.1250    0.0662     0.0000     0.2547
  Lambda Symmetric                      0.1604    0.0621     0.0388     0.2821

  Uncertainty Coefficient C|R           0.1261    0.0467     0.0346     0.2175
  Uncertainty Coefficient R|C           0.0515    0.0191     0.0140     0.0890
  Uncertainty Coefficient Symmetric     0.0731    0.0271     0.0199     0.1262