SFU Calendar 2001-2002

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Index : searchable with the Find function of your web browser Calendar .pdfs Office of the Registrar / SFU


Department of Molecular Biology and Biochemistry


8166 South Science Building, (604) 2915630 Tel, (604) 2915583 Fax, http://www.sfu.ca/mbb

Chair

M.J. Smith BSc (St. Mary's, Calif), PhD (Br Col)

Faculty and Areas of Research

D.L. Baillie - developmental genetics, genomics

T. J. Borgford - protein structure and function

B.P. Brandhorst - developmental biology and gene regulation

F.S.L. Brinkman - bacterial genomics and bioinformatics

R.B. Cornell - membrane bound enzymes

R.J. Cushley - high field nuclear magnetic resonance

W.S. Davidson - molecular, population and evolutionary genetics

N. Harden - developmental genetics, signal transduction

B.M. Honda - molecular biology and gene regulation

M.R. Leroux - protein structure and function

F.F. Pio - physical biochemistry; x-ray crystallography

W.R. Richards - protein biochemistry; photosynthesis

J.K. Scott - immunochemistry, immunology

D. Sen - nucleic acid biochemistry; chromosome structure

M.J. Smith - molecular phylogeny and development

J.L. Thewalt - membrane biophysics; nuclear magnetic resonance

P.J. Unrau - RNA-catalyzed chemical reactions; early metabolism; self-replicating systems

E. Verheyen - Drosophila developmental genetics; cell fate determination

Associate Members

E.A. Accili, Kinesiology

A.T. Beckenbach, Biological Sciences

A.J. Bennet, Chemistry

F. Breden, Biological Sciences

N.H. Haunerland, Biological Sciences

C. Krieger, Kinesiology

M.M. Moore, Biological Sciences

B.M. Pinto, Chemistry

L. Quarmby, Biological Sciences

G.F. Tibbits, Kinesiology

Obtain information about the department and its faculty research from the MBB graduate secretary, Department of Molecular Biology and Biochemistry, Simon Fraser University, 8888 University Drive, Burnaby, BC, V5A 1S6. Telephone 778.782 5631, Email mbb@sfu.ca

Admission

see "1.3 Admission". for requirements. Applicants should normally have completed some advanced course work in a related discipline.

Degree Requirements

Students will be assigned a graduate supervisory committee which has the authority to specify an appropriate program of work to meet or exceed the minimum requirements stated below. All students are expected to attend the MBB research seminar series and to participate regularly in a journal club.

MSc Program

Course Work

Minimum requirements are 12 credit hours of graduate courses including MBB 801 and 802.

Research

A major part of the MSc program will be devoted to original research. A thesis describing the work must be submitted and defended in accordance with Graduate General Regulations.

PhD Program

Course Work

For those with a BSc or equivalent, a minimum of 20 credit hours is required, at least 15 of which must be graduate level including MBB 801, 802 and 806. PhD students normally enrol in MBB 806 at the earliest opportunity following four semesters in the program. With the approval of the supervisory committee, MSc students may apply to the MBB graduate program committee for transfer to the PhD program.

For those entering with an MSc, eight credit hours are required, at least six of which must be at the graduate level including MBB 802 and 806. The latter course must be taken at the first opportunity following two semesters of program registration.

Research

A major portion of the PhD program is original research. An original thesis which contributes new knowledge is presented and defended at the program's end according to Graduate General Regulations. In addition, all MBB PhD candidates present a public seminar on their research.

Courses Offered by Other Departments

Upon the supervisory committee's recommendation and with the department graduate studies committee's approval, MBB students may take relevant courses from other departments toward their degree. Some courses of interest may include, but are not limited to CHEM 752, 754 and 811.

Graduate Course Work at Other Universities

With the supervisory committee's recommendation and department graduate studies committee approval, up to six credit hours taken elsewhere that didn't result in a degree may apply to requirements, but not exceed more than half the required credits in addition to MBB 801, 802 and 806.

Graduate Courses

MBB 801-2 Student Seminar in Molecular Biology and Biochemistry I

Discussion of recent literature through student seminars and written reports. Cannot be taken for credit in addition to CHEM 801.

MBB 802-2 Student Seminar in Molecular Biology and Biochemistry II

Discussion of recent literature through student seminars and written reports. Prerequisite: MBB 801 or an MSc degree. Cannot be taken for credit in addition to CHEM 802.

MBB 806-3 PhD Graduate Research Seminar

Oral presentation and defense of a written PhD research proposal. Students will be examined on their progress and grasp of knowledge relevant to the proposed research and their capacity to complete the proposed thesis research. Open only to students in the molecular biology and biochemistry graduate program. Cannot be taken for credit in addition to CHEM 806.

MBB 811-1, 812-2, 813-3 Techniques in Molecular Biology and Biochemistry

Consideration of methods applied to research in molecular, cellular, and developmental biology; genetics; and biochemistry. Can be repeated with permission of the instructor.

MBB 821-3 Nucleic Acids

An examination of recent literature about the structure and function of DNA and RNA.

MBB 822-3 Biological Membranes

A review of recent literature on the structure, dynamics, function and biosynthesis of membrane lipids and proteins.

MBB 823-3 Protein Structure and Function

Transition state theory; specificity in enzyme catalyzed reactions; use of recombinant DNA techniques to describe and modify enzyme catalysis, catalytic activities through monoclonal antibody techniques.

MBB 824-3 Physical Biochemistry

The physical properties of biomacromolecules; modern physical methods applied to biomolecules; properties and analysis of membrane systems.

MBB 825-3 Bioenergetics

Consideration of important processes for biological energy transduction. Structure/function relationships of membrane components and other interacting macromolecular systems. Cannot be taken for credit in addition to CHEM 825.

MBB 826-3 Molecular Immunology

An overview of cellular and humoral immunology with emphasis on the molecular basis of immune recognition and response.

MBB 827-3 Mechanisms in Enzyme Catalysis

The study of enzyme mechanisms by a variety of techniques including spectroscopic, kinetic, radioisotopic exchange, and site-directed mutagenesis.

MBB 828-3 Spectroscopic Methods in Biochemistry

Application of spectroscopic methods including multidimensional NMR, fluorescence, circular dichroism, and FTIR for determination of biomacromolecular structure. Includes elements of protein conformation. Cannot be taken for credit in addition to CHEM 828.

MBB 829-3 Special Topics in Biochemistry

Consideration of recent literature concerning selected contemporary research topics. Can be taken more than once with permission of the instructor.

MBB 831-3 Molecular Evolution of Eukaryote Genomes

Examination of the dynamics of change in eukaryotic nuclear, mitochondrial, and chloroplast genome structure and organization.

MBB 832-3 Molecular Phylogeny and Evolution

Examination of the basic methods applicable to analyses of molecular phylogeny and evolution.

MBB 833-3 Developmental Genetics

Selected topics in the developmental genetics of drosophila.

MBB 834-3 Topics in Developmental Biology

Selected topics including pattern formation, morphogenetic determinants, inductive interactions, and differential gene expression in embryos.

MBB 835-3 Genomic Analysis

Consideration of topics related to the structure and function of the genome with emphasis on genome mapping and sequencing projects, and computational methods for genomic sequence analysis.

MBB 836-3 Gene Expression

A consideration of the mechanisms and regulation of gene expression in eukaryotes and prokaryotes.

MBB 837-3 Molecular Genetics of Signal Transduction

Consideration of mechanisms of signal transduction using molecular genetic approaches with emphasis on the yeast Saccharomyces cerevisiae. Cannot be taken in addition to BISC 861.

MBB 839-3 Special Topics in Molecular Biology

Consideration of recent literature concerning selected contemporary research topics. Can be taken more than once with permission of instructor.

MBB 871-1 Directed Readings in Molecular Biology and Biochemistry

Programs of directed reading and critical discussions offered by faculty or staff members to individual students according to their needs. Study programs must be approved by the molecular biology and biochemistry graduate studies committee.

MBB 872-2 Directed Readings in Molecular Biology and Biochemistry

Programs of directed reading and critical discussions offered by faculty or staff members to individual students according to their needs. Study programs must be approved by the molecular biology and biochemistry graduate studies committee.

MBB 873-3 Directed Readings in Molecular Biology and Biochemistry

Programs of directed reading and critical discussions offered by faculty or staff members to individual students according to their needs. Study programs must be approved by the molecular biology and biochemistry graduate studies committee.

MBB 898-0 MSc Thesis
MBB 899-0 PhD Thesis


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Index : searchable with the Find function in your web browser Calendar.pdfs Office of the Registrar / SFU
Table of Contents : searchable with the Find function in your web browser Course Database or Course Outlines
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Financial Assistance