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Statistics & Acturarial Science Seminar - Celia Greenwood - Nov 14th - Thursday

Please Note: This seminar is on Thursday (not our usual day)


Celia Greenwood

Lady Davis Institute/McGill

Epidemiology, Biostatistics & Occupational Health

Montreal, Quebec


All are Welcome to the Seminar and “Meet-the-Speaker”


Date:      November 14, 2013 (Thursday)

Time:     1:30 p.m.

“Meet-the-Speaker” session directly after the talk

Room: ASB 10900

Light refreshments at 1:15 p.m. – IRMACS Lunch Room

No registration required


Identifying regions and sites of interest in DNA methylation data: an exploration of possible approaches.


Methylated DNA becomes inaccessible to binding by other molecules, and hence methylation influences gene activity and regulation. Measures of DNA methylation are now available genome-wide, and the signals can be strongly correlated over small regions. I will discuss various ideas about how to analyze DNA methylation data in a way to capture the most informative patterns in the data. Methods discussed include partial least squares analysis and functional data analysis. This is a work in progress.


Celia Greenwood is a Senior Scientist at the Lady Davis Research Institute in Montreal, and Associate Professor at McGill University. She has been working on methodology development in statistical genetics and genomics for almost 20 years, with recent contributions to methods for analysis of DNA sequencing data and rare genetic variants. Analysis of DNA methylation data is a new area of interest.