Cardiovascular and Postural Control Interactions during Hypergravity: Effects on Cerebral Autoregulation in Males and Females

Investigators: Nandu Goswami & Helmut Hinghofer-Szalkay, Medical University of Graz, Graz, Austria; Andrew Blaber, Simon Fraser University, Burnaby, Canada; Paul Avan, University of Auvergne, Clermont-Ferrand, France

Orthostatic intolerance remains a problem upon return to Earth from the microgravity environment of spaceflight. The goal of the proposed research is to further our understanding of the fundamental adaptive homeostatic mechanisms involved in gravity related changes in cardiovascular and postural function. Cardiovascular, cerebrovascular, and postural sensory motor control systems in male and female participants before, during, and after exposure to graded levels of hyper-G are being investigated.


Goswami N, Evans J, Schneider S, von der Wiesche M, Mulder E, Rössler A, Hinghofer-Szalkay H, Blaber AP. (2015) Effects of Individualized Centrifugation Training on Orthostatic Tolerance in Men and Women. PLOS One. May 28, 2015. DOI:10.1371/journal.pone.0125780

Goswami N, Bruner N, Xu D, Bareille M-P, Beck A, Hinghofer-Szalkay H, Blaber AP. (2015) Short-arm human centrifugation with 0.4G at eye and 0.75G at heart level provides similar cerebrovascular and cardiovascular responses to standing. Europ J Appl Physiol, 115(7):1569-1575 


Centrifuge: 2g at the feet

Stand test