John R. Best, PhD completed his PhD at the University of Georgia, and has since completed postdoctoral fellowships at Washington University School of Medicine in St. Louis and the University of British Columbia. Most recently, Dr. Best was a Research Associate at the University of British Columbia in the Aging, Mobility, and Cognitive Neuroscience Laboratory. Dr. Best’s research interests fall within the emerging, interdisciplinary field of health neuroscience, which aims to understand how the brain both affects and is affected by physical health. The aim of this work is to (1) gain a better understanding the modifiable risk factors for cognitive impairment and dementia, (2) identify the role of neurocognition, both independently and in interaction with environmental and social factors and incentives, in determining adherence to positive health behaviours, and (3) design lifestyle interventions that reduce dementia risk and manage its progression. This work has been supported by fellowships from the US National Institutes of Health, the Michael Smith Foundation for Health Research, and the Canadian Institutes of Health Research.
Liu-Ambrose, T., Davis, J. C., BEST, J. R., Dian, L., Madden, K., Cook, W., Hsu, C. L., & Khan, K. (2019). Effect of a home-based exercise program on subsequent falls among community-dwelling high-risk seniors after a fall: A randomized clinical trial. Journal of the American Medical Association, 321, 2092-2100.
BEST, J. R., Falck, R. S., Landry, G. J., & Liu-Ambrose, T. (2019). Analysis of dynamic, bidirectional associations in older adult physical activity and sleep quality. Journal of Sleep Research, 28, e12769.
BEST, J. R., Liu-Ambrose, T., Metti, A. L., Rosso, A. L., Satterfield, S., Studenski, S., Newman, A. B., & Rosano, C., for the Health Aging, and Body Composition Study. (2018). Longitudinal associations between walking speed and amount of time spent walking over a 9-year period in older women and men. Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 9, 1265-1271.
BEST, J. R., Rosano, C., Aizenstein, H. J., Tian, Q., Boudreau, R. M., Ayonayon, H. N., Satterfield, S., Simonsick, E. M., Studenski, S., Yaffe, K., & Liu-Ambrose, T., for the Health Aging, and Body Composition Study. (2017). Long-term changes in physical activity and subsequent structural brain changes in older adults. Neurobiology of Aging, 57, 153-161.
BEST, J. R., Chiu, B. K., Hall, P.A., & Liu-Ambrose, T. (2017). Larger lateral prefrontal cortex volume predicts better exercise adherence among older adults: Evidence from two exercise training studies. Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 72, 804-810.
Liu-Ambrose, T., BEST, J. R., Davis, J. C., Eng, J. J., Lee, P. E., Jacova, C., Boyd, L. A., Brasher, P. M., Munkacsy, M., Cheung, W., & Hsiung, G-Y. R. (2016). Aerobic exercise and vascular cognitive impairment: A randomized controlled trial. Neurology, 87, 2082-2090.
BEST, J. R., Liu-Ambrose, T., Boudreau, R. M., Ayonayon, H. N., Satterfield, S., Simonsick, E. M., Studenski, S., Yaffe, K., Newman, A. B., & Rosano, C., for the Health Aging, and Body Composition Study. (2016). An evaluation of the longitudinal, bidirectional associations between gait speed and cognition in older women and men. Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 71, 1616-1623.
BEST, J. R., Davis, J. C., & Liu-Ambrose, T. (2015). Longitudinal Analysis of Physical Performance, Functional Status, Physical Activity, and Mood in Relation to Executive Function in Older Adults Who Fall. Journal of the American Geriatrics Society, 63, 1112-1120.