X-ray crystallography, electron cryomicroscopy, computational modeling and proteomics tools are used to investigate bacterial secretion and pilus assembly systems, viral proteases and eukaryotic proteins involved in programmed cell death.
The bacterial Type IV pilus apparatus is a remarkable molecular machine that rapidly assembles and disassembles protein polymers to perform diverse functions related to microbial pathogenesis.
We are interested in genome-mutating processes.
Our main research interest is on inflammation and cell death processes and characterizing the molecular event that lead to their activation in specific conditions such as microbial infection, chronic diseases.
We are interested in studying nature's own border patrol - the cell membrane. We study the physical behavior of lipid molecules in model membranes using deuterium nuclear magnetic resonance (2H NMR) spectroscopy.