Structural Biology

X-ray crystallography, electron cryomicroscopy, computational modeling and proteomics tools are used to investigate bacterial secretion and pilus assembly systems, viral proteases and eukaryotic proteins involved in programmed cell death.

The bacterial Type IV pilus apparatus is a remarkable molecular machine that rapidly assembles and disassembles protein polymers to perform diverse functions related to microbial pathogenesis.

Email: 

LISA CRAIG
licraig@sfu.ca

Lab Room: 

SSB 7169

Lab Phone:  

(778) 782-7141

We are interested in genome-mutating processes.

Email: 

Mani Larijani
mani_larijani@sfu.ca

Please note: All position enquiries for the Larijani Lab must be directed to larijani.lab.sfu@gmail.com

Lab Room:

SSB 6159

Lab Phone: 

(778) 782-6817

We investigate enzyme structure and mechanism.

Email: 

MARK PAETZEL
mpaetzel@sfu.ca

Lab Room: 

SSB 6156

Lab Phone:

(778) 782-4318

Our main research interest is on inflammation and cell death processes and characterizing the molecular event that lead to their activation in specific conditions such as microbial infection, chronic diseases.

Email: 

FREDERIC PIO
fpio@sfu.ca

Lab Room: 

SSB 7134

Lab Phone: 

(778) 782-5657

 

We are interested in studying nature's own border patrol - the cell membrane. We study the physical behavior of lipid molecules in model membranes using deuterium nuclear magnetic resonance (2H NMR) spectroscopy.

Email:

JENIFER THEWALT
jthewalt@sfu.ca 

Lab Room:

SSB 6166/6128 

Lab Phone:

(778) 782-5489
(778) 782-4955

We create new chemical and biochemical probes of glycan processing enzymes and use these to evaluate the roles of interesting glycoconjugates in cellular processes and diseases.

Email: 

DAVID VOCADLO
dvocadlo@sfu.ca

Lab Room: 

TASC II 8060

Lab Phone: 

(778) 782-7015

Many proteins undergo changes in three-dimensional structure (conformation). My primary research interest is in understanding why and how this happens.

Email: 

EDGAR YOUNG
youngec@sfu.ca

Lab Room: 

SSB 7159

Lab Phone: 

(778) 782-5645