Simon Fraser University
Engaging the World

Course Outlines

Spring 2016 - MBB 321 D100

Intermediary Metabolism (3)

Class Number: 1806

Delivery Method: In Person

Overview

  • Course Times + Location:

    Jan 5 – Apr 11, 2016: Mon, Wed, Fri, 8:30–9:20 a.m.
    Burnaby

  • Exam Times + Location:

    Apr 15, 2016
    Fri, 12:00–3:00 p.m.
    Burnaby

  • Prerequisites:

    MBB 231, with a minimum grade of C.

Description

CALENDAR DESCRIPTION:

The enzymes and intermediates of major catabolic and anabolic pathways. Their regulation and integration in health and disease states.

COURSE DETAILS:

Lecture Topics:

  1. Review of bioenergetics, reaction mechanisms
  2. Catalysis, enzyme kinetics
  3. Carbohydrates: structure, glycogen metabolism
  4. Carbohydrates: glycolysis, citric acid cycle
  5. Carbohydrates: gluconeogenesis, pentose phosphate pathway
  6. Electron transport, oxidative phosphorylation
  7. Mitochondrial transport systems, lipid structure
  8. Lipids: beta oxidation, fatty acid biosynthesis
  9. Lipids: phospholipid biosynthesis, steroid metabolism
  10. Lipids: eicosanoid metabolism, amino acid metabolism
  11. Amino acids: urea cycle, nitrogen cycle
  12. Nucleotide biosynthesis and catabolism
  13. Metabolic regulation

Grading

  • Exam 1 20%
  • Exam 2 20%
  • Exam 3 60/80/100%
  • Mark = best possible combination of above exams.

Materials

REQUIRED READING:

Cox and Nelson, Lehninger Principles of Biochemistry, 6th edition, 2012. W.H. Freeman & Company.

Department Undergraduate Notes:

  • Students are advised to review the plagiarism tutorial found at
    http://www.lib.sfu.ca/help/tutorials/plagiarism-tutorial
  • For help with writing, learning and study strategies please contact the Student Learning Commons at
    http://learningcommons.sfu.ca/
  • Students requiring accommodations as a result of a disability, must contact the Centre for Students with Disabilities (778-782-3112 or e-mail:  csdo@sfu.ca)

Registrar Notes:

SFU’s Academic Integrity web site http://students.sfu.ca/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating.  Check out the site for more information and videos that help explain the issues in plain English.

Each student is responsible for his or her conduct as it affects the University community.  Academic dishonesty, in whatever form, is ultimately destructive of the values of the University. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the University. http://www.sfu.ca/policies/gazette/student/s10-01.html

ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS