Spring 2018 - MBB 738 G100

Human Molecular Genetics (3)

Class Number: 10590

Delivery Method: In Person

Overview

  • Course Times + Location:

    Jan 3 – Apr 10, 2018: Tue, 12:30–2:20 p.m.
    Burnaby

    Jan 3 – Apr 10, 2018: Thu, 12:30–2:20 p.m.
    Burnaby

  • Exam Times + Location:

    Apr 19, 2018
    Thu, 3:30–6:30 p.m.
    Burnaby

  • Prerequisites:

    MBB 331 (or BISC 331) or equivalent.

Description

CALENDAR DESCRIPTION:

The course will consider recent advances in human molecular genetics. Topics will include genome analysis, genetic testing, and studies of genetic disorders.

COURSE DETAILS:

This lecture and seminar course will cover the topics listed below and will integrate primary research papers into the topics.
3 lecture hours/week; 1 tutorial/week; 0 lab hours

Lecture Topics:
1. Human genetic disease inheritance
2. Molecular analysis of single gene disorders
3. Genetic analysis of complex disease
4. Gene therapy
5. Gene testing
6. Cloning and stem cells
7. Animal models of human diseases
8. Ethical considerations of human genetics
9. Genetically modified organisms and food

Grading

  • Two midterm exams (25%) 50%
  • In-class presentation 25%
  • Grant proposal 25%

Materials

RECOMMENDED READING:

Human Molecular Genetics by Strachan and Read, and Genetics and Genomics in Medicine by Strachan et al. are excellent recommended references for the material. We will also be reading papers from the primary literature.

Graduate Studies Notes:

Important dates and deadlines for graduate students are found here: http://www.sfu.ca/dean-gradstudies/current/important_dates/guidelines.html. The deadline to drop a course with a 100% refund is the end of week 2. The deadline to drop with no notation on your transcript is the end of week 3.

Registrar Notes:

SFU’s Academic Integrity web site http://students.sfu.ca/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating.  Check out the site for more information and videos that help explain the issues in plain English.

Each student is responsible for his or her conduct as it affects the University community.  Academic dishonesty, in whatever form, is ultimately destructive of the values of the University. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the University. http://www.sfu.ca/policies/gazette/student/s10-01.html

ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS