Fall 2019 - MBB 721 G100

Nucleic Acids (3)

Class Number: 1988

Delivery Method: In Person

Overview

  • Course Times + Location:

    Sep 3 – Dec 2, 2019: Tue, Thu, 10:30 a.m.–12:20 p.m.
    Burnaby

Description

CALENDAR DESCRIPTION:

An examination of recent literature about the structure and function of DNA and RNA.

COURSE DETAILS:

Recent literature is examined for insights into the structure and properties of DNA and RNA, drawing on a variety of biochemical, chemical and molecular biological perspectives.

3 lecture hours/week; 1 tutorial hour/week; 0 lab hours

Lecture Topics:
1. Sugars, bases, and nucleotides
2. DNA structure
3. Chromatin
4. Recombination structures
5. RNA structure
6. RNA - ligand (proteins and drugs) interactions
7. DNA - ligand (proteins and drugs) interactions
8. Catalytic RNA
9. RNA and the origin of life

Grading

  • 2 exams (45% each) 90%
  • Class presentations 10%

Materials

RECOMMENDED READING:

G.M. Blackburn, M.J. Gait, David Loakes, David Williams (editors).  Nucleic Acids in Chemistry and Biology, 3rd Edition, 2006. Royal Society of Chemistry.
ISBN: 978-0854046546

Graduate Studies Notes:

Important dates and deadlines for graduate students are found here: http://www.sfu.ca/dean-gradstudies/current/important_dates/guidelines.html. The deadline to drop a course with a 100% refund is the end of week 2. The deadline to drop with no notation on your transcript is the end of week 3.

Registrar Notes:

SFU’s Academic Integrity web site http://www.sfu.ca/students/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating.  Check out the site for more information and videos that help explain the issues in plain English.

Each student is responsible for his or her conduct as it affects the University community.  Academic dishonesty, in whatever form, is ultimately destructive of the values of the University. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the University. http://www.sfu.ca/policies/gazette/student/s10-01.html

ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS