Fall 2020 - HSCI 440 D100

Cell Pathophysiology Laboratory (4)

Class Number: 6322

Delivery Method: In Person


  • Course Times + Location:

    We 1:30 PM – 5:20 PM
    BLU 9650, Burnaby

  • Prerequisites:

    HSCI 321 and one of BISC 357, MBB 308, or MBB 309W.



A review of pathophysiological mechanisms of disease with an emphasis on the molecular, cellular and genetic bases of pathology. Laboratory includes cell-biology experiments, histological preparations, and microscopic examination of normal and diseased tissues.


This laboratory course is an in-person course modified for running with COVID-19 safety protocols in place.  In-person sessions in the teaching laboratory will alternate with online modules and supplementary materials for learning before and after the biweekly in-person sessions. The online components may be completed asynchronously in a self-regulated manner.  Students are expected to attend the in-person sessions unless illness or other circumstances prevent this and must comply with the safety protocols for attending the laboratory and visiting the university.


  • Explain how laboratory research techniques and experimental methodology can be used to investigate cell biology as it relates to mechanisms governing disease pathogenesis in humans.
  • Conduct mammalian cell culture-based experiments that are used to investigate mechanisms involved in cellular pathophysiology.
  • Interpret and critique the experimental observations, results, and data and relate these to current models and mechanisms of human pathophysiology.


  • Laboratory reports (2x30%) 60%
  • Online assignments (6x5%) 30%
  • Pre-lab assignments/quizzes (5x2%) 10%



Students will be required to wear personal protective equipment (PPE) in the laboratory. This includes a lab coat, face mask, disposable gloves, and safety glasses. PPE will be available in the laboratory for students, but students may bring and use their own if they choose.  The use of a laboratory notebook or binder is strongly encouraged.

Registrar Notes:


SFU’s Academic Integrity web site http://www.sfu.ca/students/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating.  Check out the site for more information and videos that help explain the issues in plain English.

Each student is responsible for his or her conduct as it affects the University community.  Academic dishonesty, in whatever form, is ultimately destructive of the values of the University. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the University. http://www.sfu.ca/policies/gazette/student/s10-01.html


Teaching at SFU in fall 2020 will be conducted primarily through remote methods. There will be in-person course components in a few exceptional cases where this is fundamental to the educational goals of the course. Such course components will be clearly identified at registration, as will course components that will be “live” (synchronous) vs. at your own pace (asynchronous). Enrollment acknowledges that remote study may entail different modes of learning, interaction with your instructor, and ways of getting feedback on your work than may be the case for in-person classes. To ensure you can access all course materials, we recommend you have access to a computer with a microphone and camera, and the internet. In some cases your instructor may use Zoom or other means requiring a camera and microphone to invigilate exams. If proctoring software will be used, this will be confirmed in the first week of class.

Students with hidden or visible disabilities who believe they may need class or exam accommodations, including in the current context of remote learning, are encouraged to register with the SFU Centre for Accessible Learning (caladmin@sfu.ca or 778-782-3112).