Overview

Description

CALENDAR DESCRIPTION:

The study of human physiological responses and adaptations to acute and chronic exercise/work. Cardiorespiratory, cellular and metabolic adaptations will be studied and discussed in detail.

COURSE DETAILS:

**The following planned schedule is tentative & subject to change**

Week	Lecture topics	Readings	Quizzes/exams	Assignments
1	Course introduction 1.1 Course experience 1.2 Bioenergetics: cellular 1.3 Bioenergetics: whole-body	Hawley 2015 Westerblad 2010	Canvas Quiz 1 (survey)
2	Assessing task demand 2.1 Muscle physiology & task demand 2.2 Applied neuromuscular physiology: motor unit & muscle fibre typing 2.3 Applied neuromuscular physiology: principles of motor unit recruitment		Canvas Quiz 2 (readings)
3	Occupational physiology 3.1 Physiology of work 3.2 & 3.3 Pre-employment tests and standards	Jamnik 2013	Canvas Quiz 3 (Jamnik, material from weeks 1-2)	Assignment 1: Occupational physiology
4	Cellular-level energy supply 4.1 Energy systems 4.2 Metabolic biochemistry 4.3 Catabolism of macronutrients
5	Systemic energy supply 5.1 Ventilatory physiology 5.2 Cardiac physiology in exercise 5.3 Vascular physiology in exercise	McKenzie 2012 Burnley & Jones 2007	Canvas Quiz 4 (McKenzie reading)	Assignment 1 due; end of midterm material
6	Midterm exam 6.1 Exam review: review study questions 6.2 Midterm in class		Midterm exam (in-class & take-home portions)
7	Defence of whole-body homeostasis 7.1 VO2max, VO2 kinetics, metabolic thresholds 7.2 Midterm recap 7.3 Principles of homeostasis, autonomic control of ventilation and cardiovascular function
8	Defence of whole-body homeostasis 8.1 Neuroendocrine responses to exercise and substrate mobilization 8.2 Sports physiology and athlete monitoring 8.3 Negative effects of exercise (adverse events, fatigue)	Davison 2009		Assignment 2: Sports physiology
9	Exercise training adaptations 9.1 Recovery kinetics 9.2 Training principles 9.3 Signal transduction principles
10	Exercise training adaptations 10.1 Cellular basis of adaptation 10.2 Muscle, metabolic, CV adaptations 10.3 Neural adaptations [possibly exercise and immunity]	Egan 2013		Assignment 2 due
11	Clinical exercise physiology 11.1 Detraining, deconditioning, disease 11.2 Interaction of exercise, diseases, and their treatments 11.3 CPET diagnostics		Canvas Quiz 5 (training adaptations)	Assignment 3: Clinical exercise physiology
12	Environmental factors modifying exercise stress & adaptations: 12. 1 Barometric pressure & hypoxia 12. 2 Temperature biophysics & measurement 12.3 Temperature physiology	Reading on CPET TBD
13	Special populations 13.1 Pediatric and older adult populations 13.2 Sex differences 13.3 Exam review			Assignment 3 due
TBD	Q&A session during exam week
Exam period	Final exam			Final exam

COURSE-LEVEL EDUCATIONAL GOALS:

1. Define, distinguish, and estimate energy, work, power, and efficiency as they apply to exercise and physically demanding tasks.
2. Predict motor unit/muscle fibre recruitment and rate coding exhibited during different muscle contraction types and exercise modalities, and the effects of modulatory factors such as fatigue.
3. Describe the biochemical processes that consume energy and those that supply energy, and the control processes that ensure they are matched.
   a. Apply bioenergetic principles (thermodynamics and kinetics) to explain and calculate cellular energy transduction during exercise.
   b. Describe how cellular-level energy consumption integrates to whole-body energy expenditure.
4. Predict the cardiovascular, ventilatory, and neuroendocrine adjustments to defend homeostasis in response to different exercise and environmental factors, in particular the mobilization and transport of oxygen, substrates, and metabolites at the whole-body level.
5. Describe the negative effects of exercise, including fatigue, muscle damage, and dehydration, and the time courses of their post-exercise recoveries.
6. Evaluate the risks of adverse events during exercise and propose mitigation strategies.
7. Describe the mechanisms of training-induced adaptations at the cellular and systems levels:
   a. Cellular: explain in detail the basis of cellular plasticity as it applies to skeletal muscle and apply the concepts to other cell types.
   b. Systems: explain in detail the cardiac, vascular, respiratory, and metabolic adaptations to training and acclimation to environmental stressors.
   c. Describe the neural adaptations to endurance, strength, and power training.
   d. Describe the effects and mechanisms of detraining and deconditioning.
8. Predict how exogenous factors (e.g., environmental factors, age & sex) modify exercise load, acute responses, and tolerance, as well as adaptations to chronic exposure.
   a. Evaluate acclimation strategies.
9. Assess the physiological demands of an occupational, recreational, or sport task and develop a valid pre-screening or job placement assessment protocol.
10. Interpret physiological data collected during exercise for prescribing training, assessing physiological function, diagnosing disease, or determining performance limiters.
    a. Select appropriate technologies to assess energy expenditure, cardiac strain, strength & power requirements, and tolerance to environmental factors.
11. Apply concepts of clinical exercise physiology to research the roles of exercise in diagnosing and treating chronic diseases.

Grading

Materials

REQUIRED READING:

RECOMMENDED READING:

REQUIRED READING NOTES: