Spring 2025 - MBB 321 D100
Intermediary Metabolism (3)
Class Number: 1380
Delivery Method: In Person
Overview
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Course Times + Location:
Jan 6 – Apr 9, 2025: Mon, Wed, Fri, 1:30–2:20 p.m.
Burnaby
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Instructor:
Ingrid Northwood
inorthwo@sfu.ca
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Prerequisites:
MBB 231, with a minimum grade of C.
Description
CALENDAR DESCRIPTION:
The enzymes and intermediates of major catabolic and anabolic pathways. Their regulation and integration in health and disease states.
COURSE DETAILS:
Lecture Topics:
- Review of bioenergetics, reaction mechanisms
- Catalysis, enzyme kinetics
- Carbohydrates: structure, glycogen metabolism
- Carbohydrates: glycolysis, citric acid cycle
- Carbohydrates: gluconeogenesis, pentose phosphate pathway
- Electron transport, oxidative phosphorylation
- Mitochondrial transport systems, lipid structure
- Lipids: beta oxidation, fatty acid biosynthesis
- Lipids: phospholipid biosynthesis, steroid metabolism
- Lipids: eicosanoid metabolism, amino acid metabolism
- Amino acids: urea cycle, nitrogen cycle
- Nucleotide biosynthesis and catabolism
- Metabolic regulation
Grading
- Exam 1 30%
- Exam 2 30%
- Exam 3 30%
- Canvas Assignment 10%
NOTES:
*Cumulative exams are held on the same day during the scheduled Final Exam timeslot
Materials
REQUIRED READING:
Nelson and Cox, Lehninger Principles of Biochemistry, 8th edition, 2021. W.H. Freeman & Company. Achieve for Lehninger Principles of Biochemistry (1-term access).
ISBN: 9781319230906
REQUIRED READING NOTES:
Your personalized Course Material list, including digital and physical textbooks, are available through the SFU Bookstore website by simply entering your Computing ID at: shop.sfu.ca/course-materials/my-personalized-course-materials.
Department Undergraduate Notes:
- For help with writing, learning and study strategies please contact the Student Learning Commons at
http://learningcommons.sfu.ca/ - Students requiring accommodations as a result of a disability, must contact the Centre for Accessible Learning (778-782-3112 or e-mail: caladmin@sfu.ca)
Registrar Notes:
ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS
SFU’s Academic Integrity website http://www.sfu.ca/students/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating. Check out the site for more information and videos that help explain the issues in plain English.
Each student is responsible for his or her conduct as it affects the university community. Academic dishonesty, in whatever form, is ultimately destructive of the values of the university. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the university. http://www.sfu.ca/policies/gazette/student/s10-01.html
RELIGIOUS ACCOMMODATION
Students with a faith background who may need accommodations during the term are encouraged to assess their needs as soon as possible and review the Multifaith religious accommodations website. The page outlines ways they begin working toward an accommodation and ensure solutions can be reached in a timely fashion.