Simon Fraser University
Engaging the World

Course Outlines

Spring 2026 - HSCI 440 D100

Cell Pathophysiology Laboratory (4)

Class Number: 2110

Delivery Method: In Person

Overview

  • Course Times + Location:

    Jan 5 – Apr 10, 2026: Thu, 1:30–5:20 p.m.
    Burnaby

  • Instructor:

    Frank Lee
    f_lee@sfu.ca
    1 778 782-8649
    Office Hours: by appointment

  • Prerequisites:

    HSCI 321, HSCI 323, and one of BISC 357, HSCI 336, MBB 308, or MBB 309W, all with a minimum grade of C-.

Description

CALENDAR DESCRIPTION:

A review of pathophysiological mechanisms of disease with an emphasis on the molecular, cellular and genetic bases of pathology. Laboratory includes cell-biology experiments, histological preparations, and microscopic examination of normal and diseased tissues.

COURSE DETAILS:

This course will provide students with hands-on experience in techniques in molecular biology, biochemistry and cell biology to investigate mechanisms involved in cellular pathophysiology.  Topics will include cell growth, apoptosis, cell differentiaion and cell migration.

COURSE-LEVEL EDUCATIONAL GOALS:

The objectives of this course are to provide students with  knowledge in research techniques that can be used to investigate topics in cell biology as it relates to biological mechanisms governing disease pathogenesis in humans.  At the end of this course students are expected to be able to discuss the basis for normal and pathological states at the molecular, cellular and tissue level.

Grading

  • Lab reports      50%
  • Tests 30%
  • Quiz 12%
  • Participation 8%

NOTES:

EXPECTATIONS / IMPORTANT NOTES: Students must bring their own lab coat to each class.  The professor may make changes to the syllabus if necessary, within Faculty / University regulations. This course is offered in lecture/lab/demonstration format. Notes from class presentations will be provided as PowerPoint presentations. Some assignments, readings and articles will be available from Canvas.

Materials

REQUIRED READING:

TEXTBOOK:  No required textbook for this course.  A course handbook will be distributed in the first class.

REQUIRED READING NOTES:

Your personalized Course Material list, including digital and physical textbooks, are available through the SFU Bookstore website by simply entering your Computing ID at: shop.sfu.ca/course-materials/my-personalized-course-materials.

Registrar Notes:

ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS

At SFU, you are expected to act honestly and responsibly in all your academic work. Cheating, plagiarism, or any other form of academic dishonesty harms your own learning, undermines the efforts of your classmates who pursue their studies honestly, and goes against the core values of the university.

To learn more about the academic disciplinary process and relevant academic supports, visit: 


RELIGIOUS ACCOMMODATION

Students with a faith background who may need accommodations during the term are encouraged to assess their needs as soon as possible and review the Multifaith religious accommodations website. The page outlines ways they begin working toward an accommodation and ensure solutions can be reached in a timely fashion.