Nano-objects for Addressing the Control of Nanoparticle Arrangement and Performance in Magnetic Hyperthermia

Synopsis

Magnetic hyperthermia has become an available anticancer therapy for a range of solid tumours, particularly in brain cancers where surgery is often limited. One current challenge of the technique is achieving therapeutic effects with a minimal amount of magnetic nanoparticles, for which improved heating abilities are continuously pursued. I will discuss the limitations of the present technique and a possible solution strategy based on the elaboration of nano-objects able to confine nanocubes in a fixed arrangement. This is considered as a way to improve the level of control of the nanoparticles and the heat they distribute to their surrounding media. I will discuss the magnetic behaviour of the arrangements and how this gives rise to the localized heating effects required for therapeutics.