Circadian Rhythms and Sleep Lab
 
   
       
 
 
 
 
 
 
 
 
 

Publications

2009

Mistlberger RE, Kent BA, Landry GJ. Phenotyping food-entrainment: motion sensors and telemetry are equivalent. J Biol Rhythms 24(1):xx-xx, 2009.

Meerlo P, Mistlberger RE, Jacobs BL, Heller HC, McGinty D. New neurons in the adult brain: the role of sleep and consequences of sleep loss. Sleep Medicine Reviews, in press, 2009.

2008

Mistlberger RE, Yamazaki S, Pendergast JS, Landry GJ, Takumi T, Nakamura W. Comment on ' Differential rescue of light-and food-entrainable circadian rhythms. Science 322(5901):xxx 2008

McLaughlin C, Bowman ML, Bradley CL, Mistlberger RE. A prospective study of seasonal variation in shiftwork tolerance. Chronobiology International, 25(2):455-470, 2008.

Mueller AD, Pollock MS, Lieblich SE, Epp J, Galea LAM, Mistlberger RE. Sleep deprivation can suppress hippocampal neurogenesis independent of adrenal stress hormones. American Journal of Physiology 294(5):R1693-703, 2008.

Webb IC, Patton DF, Hamson D, Mistlberger RE. Neural correlates of arousal-induced circadian clock resetting:Hypocretin/orexin and the intergeniculate leaflet. European Journal of Neuroscience, 27(4):828-35. 2008.

Mistlberger RE. Food entrainment. In: Binder, M.D, Hirokawa, N, Windhorst, U (eds). Encyclopedia of Neuroscience. Springer, Berlin Heidelberg New York 2008

Mistlberger RE. Internal desynchrony. In: Binder, M.D, Hirokawa, N, Windhorst, U (eds). Encyclopedia of Neuroscience. Springer, Berlin Heidelberg New York 2008

2007

Landry GJ, Mistlberger RE. Food-entrainment: methodological issues. Journal of Biological Rhythms, 22(6):484-487, 2007.

Landry GJ, Yamakawa GR, Webb IC, Mear  RJ, Mistlberger RE. The dorsomedial hypothalamic nucleus is not necessary for the expression of circadian food-anticipatory activity in rats. Journal of Biological Rhythms, 22(6): 467-478, 2007.

Landry GJ, Yamakawa GRS, Mistlberger RE.  Robust food anticipatory circadian rhythms in rats with complete ablation of the thalamic paraventricular nucleus. Brain Research, Apr 13;1141:108-18, 2007.

2006

Mistlberger RE.  Circadian rhythms: PERturbing a food-entrained clock. Current Biology,  16(22):R968-969, 2006.

Mistlberger RE. Editorial focus: Illuminating serotonergic gateways for strong resetting of the mammalian circadian clock. American Journal of Physiology, 291:R177-179, 2006.

Mistlberger RE, Antle MC. The enigma of behavioral inputs to the circadian clock: A test of function using restraint. Physiology and Behavior, 87(5):948-54, 2006.

Webb IC, Pollock MS, Mistlberger RE. Modafinil [(Diphenylmethyl)sulfinyl]acetamide] and circadian rhythms in Syrian Hamsters: assessment of the chronobiotic potential of a novel alerting Compound. Journal of Pharmacology and Experimental Therapeutics, 317(2):882-9, 2006.

Mistlberger RE, Webb IC, Simon MM, Tse D, Su C. Effects of food deprivation on locomotor activity, plasma glucose and circadian clock resetting in Syrian hamsters. Journal of Biological Rhythms,  21(1):33-44, 2006.

Landry GJ, Simon M, Webb IC, Mistlberger RE. Persistence of a behavioral food anticipatory circadian rhythm following dorsomedial hypothalamic ablation in rats. American Journal of Physiology, 290(6):R1527-34, 2006.

2005

Landry GS and Mistlberger RE. Differential effects of constant light on circadian clock resetting by photic and nonphotic stimuli in Syrian hamsters. Brain Research, 1059:52-58, 2005

Mistlberger RE. Circadian regulation of mammalian sleep: role of the suprachiasmatic nucleus. Brain Research Reviews, 49(3):429-454, 2005.

Mistlberger RM and Skene DJ. Nonphotic entrainment in humans? Journal of Biological Rhythms 20(4):339-352, 2005

Pollock MS, Mistlberger RE. Microinjection of neostigmine into the pontine reticular formation of the mouse: Further evaluation of a proposed REM sleep enhancement technique. Brain Research, 1031:253-267, 2005.

Mistlberger RE, Rusak B. Circadian rhythms in mammals: Formal properties and environmental influences. In: Principles and Practise of Sleep Medicine, Fourth Edition, MH Kryger, T Roth, WC Dement (eds),  W.B. Saunders Co: Philadelphia, pp. 321-334, 2005 (substantially revised and updated from Third Edition)

Mistlberger RE, Rusak B.  Biological rhythms and behavior. In Animal Behavior, J.J.Bolhuis, L-A, Giraldeau (Eds.), Blackwell Publishing,  pp. 71-96, 2005.

2004

istlberger RE,  Skene DJ. Social influences on mammalian circadian rhythms: animal and human studies. Biol Rev Camb Philos Soc. 79(3):533-56, 2004.

Knoch M, Gobes S, Pavlovska I, Su C, Mistlberger RE, Glass JD. Brief exposure to constant light promotes strong (Type 0) circadian phase resetting responses to nonphotic stimuli in Syrian hamsters. European Journal of Neuroscience, 19:2779-2790, 2004.

Holmes MM, Galea L, Mistlberger RE, Kemperman G. Adult hippocampal neurogenesis and voluntary running activity: circadian and dose dependent effects. Journal of Neuroscience Research, 76:216-222, 2004.

Antle MC, Mistlberger RE. Circadian rhythms. The Behaviour of the Laboratory Rat: A handbook with tests, IQ Whishaw, B Kolb (Eds.), MIT press,  2004 (trade book)

2003

Mistlberger RE, Antle MC, Webb IC, Jones M, Weinberg J, Pollock MS. Circadian clock resetting by arousal: The role of stress and activity. American Journal of Physiology. 285(4):R917-25, 2003

Mistlberger RE, Antle M.C., Kilduff  T.S.,  Jones M.  Food-  and light-entrained circadian rhythms in rats with hypocretin-2-saporin ablations of the lateral hypothalamus. Brain Research, 980: 161-168, 2003.

Antle MC, Ogilivie M,  Pickard GE, Mistlberger RE. Response of the mouse circadian system to 5HT1a/2/7 agonists in vivo: Surprisingly little. Journal of  Biological Rhythms, Apr;18(2):145-58, 2003.

Pollock MS, Mistlberger RE.  Rapid eye movement sleep induction by microinfusion of the GABA-A antagonist bicuculline into the dorsal subcoeruleus area of the rat. Brain Research, 962:68-77, 2003.

2002

Mistlberger RE, Belcourt J, Antle MC.  Circadian clock resetting by sleep deprivation without exercise: Dark pulses revisited.  Journal of  Biological Rhythms , 17(3):227-237, 2002.

Antle MC, Ludgate S, Mistlberger RE.  Effects of melatonin on circadian phase and nonphotic phase resetting in hamsters. Neuroscience Letters, 317(1):5-8, 2002.

Mistlberger RE.  Circadian Rhythms. In: Encyclopedia of Cognitive Science, Macmillan Reference Ltd: London,  2002. (Encyclopedia)

2001

Mistlberger RE, Antle MC, Oliverio, Coffman, Morris M. Angiotensin 1a receptor null mutation: Effects on circadian rhythms in the mouse. Physiology and Behavior, 74(4-5):457-464, 2001.

Mistlberger, RE, Marchant EG, Kippin TE. Food-entrained circadian rhythms in rats are insensitive to deuterium oxide. Brain Research, 919: 283-291, 2001.

Antle MC, Steen NM, Mistlberger RE.  Adenosine and nonphotic phase resetting of circadian rhythms in hamsters Neuroreport, 12(13):2901-5, 2001.

Mistlberger RE. Circadian Clocks, In: The Discovery of Time, S. McCready (ed), MQ Publications, London, 2001. (popular science)

2000

Antle MC, Mistlberger RE Circadian clock resetting by sleep deprivation without exercise in the Syrian hamster. Journal of Neuroscience 20(24):9326-32, 2000.

Antle MC, Glass JD, Mistlberger RE. 5-HT1a autoreceptor antagonist-induced 5-ht release in the hamster suprachiasmatic nuclei: effects on Circadian clock resetting. Neuroscience Letters, 282:97-100, 2000.

Grossman G, Mistlberger RE, Antle MC,  Glass JD. Sleep deprivation stimulates serotonin release in the suprachiasmatic nucleus. NeuroReport, 11:1929-32, 2000.

Holmes MM,  Mistlberger RE. Regulation of circadian phase by restricted feeding in the BALBc mouse. Physiology and Behavior, 68:655-666, 2000.

Klerman EB, Boulos Z, Edgar DM, Mistlberger RE, Moore-Ede MC. EEG-delta activity during undisturbed sleep in the squirrel monkey. Sleep Research OnLine, 3(3):113-119, 2000.

Mistlberger RE, Holmes MM. Behavioral feedback regulation of circadian rhythm phase angle in light-dark entrained mice. American Journal of Physiology, 279:R813-821, 2000.

Mistlberger RE,  Antle MC,  Glass JD,  Miller, JD. Behavioral and serotonergic regulation of circadian rhythms. Biological Rhythm Research, 31:240-283, 2000.

Harrington ME, Mistlberger RE. Anatomy and physiology of the mammalian circadian system. In: Principles and Practise of Sleep Medicine, Third Edition, MH Kryger, T Roth, WC Dement (eds),  W.B. Saunders Co: Philadelphia, pp. 334-345 2000. (medical textbook; revised and updated from Edition 2)

Mistlberger RE, Rusak B. Circadian rhythms in mammals: Formal properties and environmental influences. In: Principles and Practise of Sleep Medicine, Third Edition, MH Kryger, T Roth, WC Dement (eds),  W.B. Saunders Co: Philadelphia,  pp. 321-333,  2000 (medical textbook; revised and updated from Edition 2)

1999

Mistlberger RE, Antle MC. Neonatal MSG alters photic masking and circadian organization of feeding and food anticipatory activity in the rat. Brain Research, 842:73-83, 1999.

Mistlberger RE,  Holmes MM. Morphine-induced activity attenuates phase shifts to light pulses in C57BL/6j mice. Brain Research, 829:113-119, 1999.

Mistlberger RE, Marchant EG. Enhanced food anticipatory circadian rhythms in the genetically obese Zucker rat. Physiology and Behavior, 66:329-335, 1999.

Sur S, Li P, Mistlberger RE, Morris M. Circadian blood pressure and heart rate rhythms in mice.  American  Journal of  Physiology,  276:R500-504, 1999.

Klerman EB, Boulos Z, Edgar DM, Mistlberger RE, Moore-Ede MC. Circadian and homeostatic contributions to sleep timing and EEG content after sleep deprivation in the squirrel monkey. Sleep, 21:45-59, 1999.

1998

Antle MC, Marchant EG, Niel L, Mistlberger RE. Serotonin antagonists do not attenuate activity-induced phase shifts of circadian rhythms in the Syrian hamster. Brain Research, 813:139-149, 1998.

Mistlberger RE, Bossert JM, Holmes MM, Marchant EG. Serotonin and feedback effects of behavioral activity on circadian rhythms in mice. Behavioral Brain Research, 96:93-99, 1998.

Mistlberger, RE, Lukman H., Nadeau BG. Circadian rhythms in the Zucker obese rat: assessment and intervention. Appetite,  30: 255-267, 1998.

Mistlberger RE,  Antle MC.  Inhibition of light-induced circadian phase resetting by running activity is phase and serotonin dependent. Brain Research, 786:31-38, 1998.

1997

Mistlberger, R.E., Landry, G., Marchant, E.G. Sleep deprivation can attenuate light-induced phase shifts of circadian rhythms in hamsters. Neuroscience Letters 238: 5-8, 1997.

Sinclair SV, Mistlberger RE. Activity reorganizes circadian phase of Syrian hamsters under full and skeleton photoperiods. Behavioral Brain Research  87:127-137, 1997.

Marchant EG, Watson NV, Mistlberger RE. Both neuropeptide Y and serotonin are necessary for entrainment of circadian rhythms in mice by daily treadmill running schedules. Journal of Neuroscience, 17:7974-7987, 1997.

Marchant EG,  Mistlberger RE. Anticipation and entrainment to feeding time in intact and SCN-ablated C57BL/6j mice. Brain Research., 765:273-282,1997.

Mistlberger RE, Sinclair SV, Marchant EG, Neil L. Circadian phase shifts to food deprivation and refeeding in the Syrian hamster are mediated by running activity.  Physiology and Behavior, 61: 273-278, 1997.

1996

Mistlberger, RE., de Groot MH, Bossert J, Marchant EG. Discrimination of circadian phase in intact and SCN ablated rats.  Brain Research,739: 12-18, 1996.

Marchant EG, Mistlberger RE. Entrainment and shifting of circadian rhythms in mice by forced treadmill running. Physiology and Behavior, 60:657-663, 1996.

Mistlberger, RE,  Marchant EG, Sinclair SV. Nonphotic phase shifting and the motivation to run: Cold exposure reexamined. Journal of Biological Rhythms 11:208-215, 1996.

Mistlberger RE.  Aschoff type II method: Commentary. Chronobiology International, 13:393-394, 1996.

Mistlberger RE.  Circadian organization of locomotor activity in rodents. In: Motor Activity and Movement Disorders.  Paul R. Sanberg,  Klaus-Peter Ossenkopp, Martin Kavaliers; Humana Press Inc., Totowa, NJ, 1996, pp. 81-109. (trade book)

1995

Marchant EG, Mistlberger RE. Morphine phase shifts circadian rhythms in mice: Role of behavioral activation.  NeuroReport,  7:209-212, 1995.

Mistlberger RE, Marchant EG . Computational and entrainment models of circadian food-anticipatory activity: Evidence from non-24 h feeding schedules. Behavioral Neuroscience,  109:790-798, 1995.

1994

Mistlberger RE.  Circadian food anticipatory activity: Formal models and physiological mechanisms. Neuroscience and Biobehavioral Reviews, 18: 171-195, 1994.

Mistlberger RE, Rusak B. Circadian rhythms in mammals: Formal properties and environmental influences. In: Principles and Practise of Sleep Medicine, Second Edition, MH Kryger, T Roth, WC Dement (eds),  W.B. Saunders Co: Philadelphia,  1994, pp. 277-285. (medical textbook; revised and updated from Edition 1)

Harrington ME, Rusak B, Mistlberger RE. Anatomy and physiology of the mammalian circadian system. In: Principles and Practise of Sleep Medicine, Second Edition, MH Kryger, T Roth, WC Dement (eds),  W.B. Saunders Co: Philadelphia, 1994, pp. 286-300. (medical textbook)

1993

Mistlberger RE.  Effects of scheduled food and water access on circadian rhythms of hamsters in constant light, dark, and light:dark.  Physiology and Behavior, 53:509-516, 1993.

Mistlberger RE,  Circadian properties of anticipatory activity to restricted water access in suprachiasmatic nuclei ablated hamsters. American Journal of Physiology,  264:R22-29, 1993.

1992

Mistlberger RE, Nadeau J.  Ethanol and circadian rhythms in the Syrian hamster: Effects on entrained phase, reentrainment rate and period. Pharmacology, Biochemistry and Behavior, 43:159-165, 1992.

Mistlberger RE,  Anticipatory activity rhythms under daily schedules of water access in the rat. Journal of Biological Rhythms, 7:149-160, 1992.

Mistlberger RE, Mumby D.  The limbic system and food-anticipatory circadian rhythms in the rat: Ablation and dopamine blocking studies. Behavioral Brain Research, 47:159-168, 1992.

Mistlberger RE, Non-photic entrainment of circadian activity rhythms in suprachiasmatic nuclei-ablated hamsters. Behavioral Neuroscience, 102:192-202, 1992.

1991

Mistlberger RE, Scheduled daily exercise or feeding alters the phase of photic entrainment in syrian hamsters.  Physiology and Behavior,  50:1257-1260, 1991.

Mistlberger RE, Houpt TA, Moore-Ede MC.  The benzodiazepine triazolam phase shifts circadian activity rhythms in a diurnal primate, the squirrel monkey (Saimiri sciureus). Neuroscience Letters, 124:27-30, 1991.

Mistlberger RE.  Effects of daily schedules of forced activity on free-running circadian rhythms in the rat. Journal of Biological Rhythms,  6:71-80, 1991.

1990

Mistlberger RE, Houpt TA, Moore-Ede MC. Characteristics of food entrained circadian rhythms in rats during long-term exposure to constant light. Chronobiology International, 7:383-391, 1990.

Mistlberger RE, Houpt TA, Moore-Ede MC. The effects of aging on food entrained circadian rhythms in the rat. Neurobiology of Aging, 11:619-624, 1990.

Mistlberger RE. Circadian pitfalls in experimental paradigms employing food restriction. Psychobiology, 18:23-29,1990.

Mistlberger RE, Houpt TA, Moore-Ede MC. Food-anticipatory rhythms under 24 h schedules of limited access to single macronutrients.  Journal of  Biological Rhythms, 5:35-46,1990.

1989

Mistlberger R, Rusak B. Mechanisms and models of the circadian timekeeping system. In: Principles and Practise of Sleep Medicine, MH Kryger, T Roth, WC Dement (eds),  W.B. Saunders Co: Philadelphia, 1989, pp 141-152 (medical textbook)

1988

Rusak B, Mistlberger RE, Losier B, Jones CH. Daily hoarding opportunity  entrains the pacemaker for hamster activity rhythms. Journal of Comparative Physiology A, 164:165-171, 1988.

Mistlberger RE, Rusak B. Food anticipatory circadian rhythms in paraventricular and lateral hypothalamic lesioned rats. Journal of  Biological Rhythms, 3:277-292, 1988.

Rechtschaffen A, Bergmann, BM, Mistlberger, RE.  Importance of both amplitude and incidence measures in time-domain analysis.  Sleep, 11:572, 1988.

1987

Mistlberger RE, Rusak B. Palatable daily meals entrain anticipatory activity rhythms in free-feeding rats: Dependence on meal size and nutrient content. Physiology and Behavior, 41:219-226, 1987.

Mistlberger RE, Bergman B, Rechtschaffen A. Period/amplitude analysis of EEG in intact and suprachiasmatic nuclei lesioned rats: Effects of sleep deprivation and exercise. Sleep, 10:508-522, 1987.

Mistlberger RE, Bergman B, Rechtschaffen A. Relationships among wake episode lengths, contiguous sleep episode lengths and electroencephalographic delta waves in rats with suprachiasmatic nucleus lesions. Sleep, 10:12-24, 1987.

Bergman B, Mistlberger RE, Rechtschaffen A. Period/amplitude analysis of EEG in the rat: Diurnal and stage variations and effects of suprachiasmatic nuclei lesions. Sleep, 10:523-5366, 1987.

1986

Mistlberger RE, Rusak B. Carbachol induced phase shifts of circadian activity rhythms in ovariectomized rats. Neuroscience Letters, 72:357-362, 1986.

1985

Mistlberger RE, Rechtschaffen A. Restricted water access is not a potent zeitgeber for circadian locomotor rhythms in the rat. Physiology and Behavior, 34:17-22, 1985.

1984

Mistlberger RE, Rechtschaffen A. Recovery of anticipatory activity to restricted feeding in ventromedial hypothalamic lesioned rats. Physiology and Behavior, 33:227-235, 1984.

Eastman C, Mistlberger RE, Rechtschaffen A. Suprachiasmatic nuclei lesions eliminate circadian temperature and sleep rhythms in the rat. Physiology and Behavior, 32:357-368, 1984.

1983

Mistlberger R, Bergmann B, Waldenar W, Rechtschaffen A. Recovery sleep following sleep deprivation in normal and suprachiasmatic nuclei lesioned rats. Sleep, 6:217-233, 1983.