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Principal Investigators (PIs) who consider it necessary to use vertebrates or cephalopods in their research, teaching or testing in the laboratory or in the field, must first apply to the UACC for an animal care protocol. Only when approval is granted may the research involving use of animals begin.

PIs are responsible for adhering to CCAC Guidelines and should be familiar with CCAC's Ethics of Animal Investigation. Applications that have not been Peer Reviewed for scientific merit must have an independent Peer Review completed, which is facilitated by the Office of the Vice President, Research and International.

You can start this process by emailing

PIs are reminded to download an application form from this site for each submission. Electronic submissions (in Word) should be emailed to  


Additional Information

Canadian Council on Animal Care
The Canadian Council on Animal Care (CCAC) is a not-for-profit organization, created in 1968 to oversee the ethical use and care of animals in science (research, teaching and testing) throughout Canada.

Replacement, Reduction, and Refinement
The Three Rs concept originated from the scientific community and is a widely accepted cornerstone of policies on animal-based science around the world. Ethical animal use requires consideration of animal welfare needs.

Categories of Invasiveness
The use of animals in research, teaching, and testing is acceptable ONLY if it promises to contribute to understanding of fundamental biological principles, or to the development of knowledge that can reasonably be expected to benefit humans or animals.

Last updated: August 4, 2021