Dr. Mani Larijani
Assoc Prof, Dept of Molecular Biology & Biochemistry
Biological Mechanisms of Disease
Dr. Larijani's research program explores processes that mutate and alter the genetic codes of DNA/RNA, with an ultimate goal of understanding these processes and how they impact biological function. Depending on the species, these processes have biological functions such as modulating immune responses, precipitating and aggravating cancer, inducing the evolution of host and viral genomes, and affecting developmental reprogramming and tissue differentiation. Two driving interests of his lab group are how DNA/RNA-mutating processes impact human health and how these processes evolved to their present-day role from their functional origins in non-human species of the distant past. Broad though it is, the scope of his research is made possible by the Larijani lab's mastery of interdisciplinary methods, and their integration of expertise from areas ranging from biochemistry to computational biology.