Complete the sentence with the best term. Please note that if your answer is not spelled correctly, the program will note it as incorrect.
Beta cells of the pancreatic islets secrete the hormone _________________.
Alpha cells of the pancreatic islets secrete the hormone _______________.
Delta cells of the pancreatic islets secrete the hormone _______________________.
Beta cells of the pancreas are electrically coupled by _______ __________________.
In the golgi apparatus, _________________ enzymes cleave proinsulin in two sites, yielding insulin and C peptide.
Beta cell secretory granules contain equimolar amounts of insulin and ___ ____________.
About 60% of insulin secreted by the beta cells is extracted by the __________ in the first pass of the circulation.
What molecule is measured to determine the amount of insulin secreted by the beta cells?
In the secretory granules of beta cells, insulin associated with the mineral __________.
Name the protein by which glucose enters beta cells.
In the beta cells, which ion channels close to cause beta cell depolarization?
Beta cell depolarization cause influx of ______________ ions.
The insulin receptor on liver, muscle and adipocytes contains a _________ ___________ that is capable of autophosphorylation.
T cell infiltration of beta cells is known as ______________________.
The Nobel Prize in Medicine or Physiology for the "discovery of insulin" was awarded to John James McCleod and _____________________________ in 1923.
The normal molar insulin/glucagon ratio is ___________.
Drugs called _________________________ close the ATP dependant K+ channel of the beta cell and are used to increase insulin secretion.
One postulated mechanism by which insulin resistance occurs is that elevated fatty acids in the target cell cytosol cause _____________ phosphorylation fo IRS-1.
The decrease in insulin receptors on target cells in response to chronically high levels of insulin is called _______________________________.
Type I diabetes is considered an autoimmune disease in which pancreatic beta cells are destroyed by _______________________.
Elevated blood insulin levels are referred to as _______________________.
__________________ refers to the presence of ketones in the urine.
Excessive thirst is called _________________________.
The increased urine production characteristic of the acute onset of Type I diabetes is called __________________.
An increased appetite associated with the acute onset of Type I diabetes is called ____________________.