Sunday, June 3, 2007

Time Event
16:00-18:00 Registration (West Mall Complex 3210)
18:00-18:05 Welcome and official opening of the conference
18:05-18:15 Welcome remarks by Dr. Mario Pinto, Vice President, Research
18:15-19:30 Keynote lecture (R. Hegele, Western Ontario): Genomics and phenomics of disordered lipid and lipoprotein metabolism
19:30-22:00 Reception and socializing

Monday, June 4, 2007

Session 1 Structure and evolution of lipid binding proteins
Session leaders: N. Haunerland and J. Storch
Time Topic
08:30-08:50 Diversity of LBPs - an evolutionary perspective (N. Haunerland, SFU)
08:50-09:10 Genesis and fate of duplicated LBP genes of zebrafish (J. Wright, Dalhousie)
09:10-09:40 Insect sterol carrier proteins: divergent functions (Q. Lan, Wisconsin)
09:40-10:00 Circulatory lipid transport: lipoprotein assembly and function in an evolutionary perspective (D. van der Horst, Utrecht)
10:00-10:30 Coffee break
10:30-11:00 Unique functions of enterocyte fatty acid-binding proteins (J. Storch, Rutgers Univ.)
11:00-11:20 The importance of skeletal muscle FAT/CD36, FABPpm and FABPc for long distance migration in birds (J.T. McFarlan, Western Ontario)
11:20-11:40 Molecular dynamics simulations of palmitate entry into the hydro-phobic pocket of the Fatty Acid Binding Protein (H. Gutman, Tel Aviv)
11:40-12:10 Perspectives of the structure of lipid binding proteins (L. Banaszak, Minnesota)
12:10-14:00 Lunch and poster session
Session 2 Uptake of fatty acids and other lipophilic compounds
Session leaders: J. Glatz and H. Davis
Time Topic
14:00-14:30 New insights in contraction signaling towards CD36 translocation and fatty acid uptake in the heart (Joost Luiken, Maastricht)
14:30-14:50 Fatty acid uptake driven by acyl-CoA synthetases localized to different subcellular compartments (J. Fuellekrug, Heidelberg)
14:50-15:20 Uptake of intestinal sterols, role of NPC1L1 and ezetimibe (H. Davis, Schering)
15:20-15:40 Coffee break
15:40-16:00 Sterol carrier protein of Yarrowia lipolytica transfers fatty acids to acceptor membranes through a collision-mediated mechanism (L. Falomir-Lockhart, La Plata, Argentina)
16:00-16:20 Yeast Oxysterol-binding proteins: Sterol transporters or regulators of cell polarization? (C. Beh, SFU)
19:00-22:00 Banquet at the Diamond Alumni Centre

Tuesday, June 5, 2007

Session 3 Lipid metabolism and disease
Session leaders: D. Bernlohr and Y. Owada
Time Topic
08:30-09:00 Why lipids are important in Alzheimer's Disease (C. Wellington, British Columbia)
09:00-09:30 Lipid activated transcription factor control bile acid metabolism (O. Barbier, Laval)
10:00-10:30 Coffee break
10:30-11:00 Brain-type fatty acid binding protein as a key molecule for the emotional behavior (Y. Owada, Yamaguchi Univ.)
11:00-11:20 α-Synuclein is a key mediator of brain fatty acid metabolism and inflammatory response (E. Murphy, North Dakota)
11:20-11:40 Altered Saturated Fat and Cholesterol Metabolism in Liver Fatty Acid Binding Protein Null Mice (E. Newberry, Washington Univ.)
11:40-12:00 A potential role for lipid binding proteins in the absorption of lipophilic drugs (M. Scanlon, Monash Univ.)
12:00-14:00 Lunch and poster session
Session 4 LBP, integration and coordination of lipid metabolism
Session leaders: L. Agellon and F. Spener
Time Topic
14:00-14:30 Intracellular FABPs, sensors and regulators of cellular metabolism (D. Bernlohr, Minnesota)
14:30-15:00 Lipid Droplet Associated Proteins and the Control of Triacylglycerol Metabolism (D.L. Brasaemle, New Jersey)
15:00-15:30 Coffee break
15:30-16:00 Lipid binding proteins and lipidomics - a challenge and perspective (F. Spener. Graz)
16:00-16:30 Reassessing the postulated roles of iLBPs (L. Agellon, Alberta)
16:30-17:00 Closing remarks and adjournment

Poster Presentations

  1. Examining the fate of duplicated regions in the atlantic salmon (Salmo salar) genome using FABP2 genes (Y. Lai, SFU)
  2. Molecular Mechanisms of Binding of Cholesterol to Sterol Carrier Protein-2 (J. Radek, Wisconsin)
  3. The ligand-bound X-ray structure of Aedes aegypti Sterol Carrier Protein-2 Like-3 at 1.4-Angstrom Resolution (David Dyer, Wisconsin)
  4. Isolation, characterization and developmental profile of the single FABP in Drosophila melanogaster. (J.M. Stewart, Mount Allison Univ.)
  5. Molecular cloning and characterization of two novel Mesocestoides corti FABPs. (A. Esteves, Montevideo)
  6. Interaction of the locust FABP promoter with RXR (L. Cui, SFU)
  7. A sensitive method for the detection and quantification of lipid binding protein expression from small samples (J. Rickers-Haunerland, SFU)
  8. VHDL, a lipid storage protein in insect fat body, is a member of the vitellogenin gene family (H. Sum, SFU)
  9. IFABP expression alters the intracellular distribution of the BODIPY C16 fatty acid analogue (M. Gastaldi, Marseille)
  10. Molecular dynamics simulation acid-ligand of toad liver for the complete entry of fatty FABP, through the portal region (E. Nachleil, Tel Aviv)
  11. Identification of potential protein binding partners for rat L-FABP. (S.G. Chang, Mount Allison Univ.)
  12. Localization of epidermal-type fatty acid binding protein (E-FABP) in thymic epithelial cells of adult mouse (Y. Adachi, Yamaguchi University)
  13. Localization of fatty acid binding proteins (FABP) in the retina of adult mice under normal and light-exposure conditions (M. Nourani, Baqiyatallah Univ.)
  14. Expression of FABPs in human malignant glioma cells and the role of FABP7 on tumor cell growth (R.Z. Liu, Alberta)
  15. B-FABP expression in malignant glioma cells enhances their migration (R. Mita, Alberta)
  16. Serum concentrations of intestinal fatty acid-binding protein (I-FABP) in healthy volunteers and acute enteritis patients by a new sandwich ELISA system (H. Funaoka, DS Pharma Biomedical Co.)
  17. The role of fatty acid binding proteins in the fetal programming of cardiovascular disease and diabetes associated with adolescent pregnancies (L. McDermott, Kings College)
  18. AMPK-mediated increase in myocardial fatty acid uptake critically depends on sarcolemmal CD36 (J. Glatz, Maastricht)
  19. Contractions but not AICAR increase FABPpm protein content in sarcolemma (J. Jeppesen, Copenhagen)
  20. Alpha-linolenic acid inhibits FATP4 ACS. (K. Higashi, Meij Pharmac. Univ)
  21. Localization of diacylglycerol kinase γ and -ε in neurons (Y. Hozumi, Yamagata Univ.)
  22. Pro-atherogenic effects of probucol in apo E-KO mice are associated with alterations in physico-chemical properties of lipoproteins (M. H. Moghadasian, U Manitoba)

Please note: Only the presenting author is listed on the program pages.The full list of authors for each paper and their affiliations is included with the abstracts.