My laboratory is interested in developing bioinformatics programs and genomics
(and molecular) tools for understanding genome architecture and expression.
In particular, we are interested in characterizing gene structures,
transcription factors and regulatory elements, sequence and structural
variations, and, more importantly, regulatory mechanisms. Ultimately,
we are interested in
understanding how genome sequences and their organization (including
various modifications) direct development and biological functions.
Currently, we primarily use the nematode Caenorhabditis elegans as a
model system. Bioinformatics programs and genomics tools, however, are
generally readily applicable in all organisms, ranging from bacteria to humans.
Current research projects fall into two major categories: (1) Identification
and characterization of novel genes, synteny blocks, functional elements,
genome variations and genome rearrangements; (2) Transcriptional regulation of
genes and gene batteries.
My research group provides an ideal environment for students who have interest in the emerging field of genomics
and bioinformatics, an exciting field which is developing essentially everyday. Within this group, students have the
opportunity to learn and apply computational skills, as well as advanced genomics and molecular techniques. Check current
projects in my laboratory. If you find any one interesting to you, send me a message.
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