Coast to Coast Seminar Series: "Aging in Individuals and Populations/Mathematical Modeling"

Abstract

Aging and its complexity, and regularities- the Gompertz law of mortality. Chronological vs. biological aging. Aging as a process of deficits accumulation. The frailty index as a proxy-measure of individual and population aging. The concept of equality of health deficits. Phenomenological invariants of aging: aging rates; sex-related differences; limit in the deficits accumulation; compensation laws of mortality and deficits accumulation. Stochastic dynamics of age trajectories. Irreversibility of chronological aging and local reversibility of biological aging. What is the law that governs changes in health during aging? Aging, health and wealth, how they are related world wide.