Spring 2016 - BISC 302W D100
Genetic Analysis (3)
Class Number: 2491
Delivery Method: In Person
Overview
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Course Times + Location:
Jan 5 – Apr 11, 2016: Tue, Thu, 10:30–11:20 a.m.
Burnaby -
Exam Times + Location:
Apr 13, 2016
Wed, 3:30–6:30 p.m.
Burnaby
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Instructor:
Kathleen Fitzpatrick
kathleef@sfu.ca
778.782.5611
Office: B8233
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Prerequisites:
BISC 202 with a grade of C- or better.
Description
CALENDAR DESCRIPTION:
Discussion and manipulations of some of the organisms and techniques applicable to genetic analysis. Students are required to come into the lab on average of two hours per week in addition to the four hour scheduled lab each week for project work. Students with credit for BISC 302 may not take this course for further credit. Writing.
COURSE DETAILS:
Lecture/Laboratory course using model eukaryotes. We will assume you understand the basics of genes, gene mapping, recombination and segregation from Bisc 202. YOU WILL NOT HAVE AN EASY TIME IN THIS COURSE WITHOUT THIS BASIC UNDERSTANDING!!!
The laboratory will include experiments involving several model organisms, including corn, Drosophila, Sordaria (a filamentous fungus), and case studies involving human genetics scenarios. A major project with Drosophila will be required of each student. The work for the project will be done in groups of 3 to 5. The project requires some time in the lab outside of regular lab times.
Experiments will include gene mapping, using standard genetic crosses, as well as tetrad analysis. Students may examine chromosomes preparations from selected organisms. Other labs will cover extraction of DNA, and PCR (polymerase chain reaction) amplification of selected DNA regions. T
he lecture topics will include a review of standard genetic mapping, advanced mapping and tetrad analysis, mechanisms of recombination, gene conversion, epigenetics, transposable elements, sex-linkage including its origins and evolution, and forward and reverse genetic approaches. The final lecture(s) may cover student-selected topics.
This is a writing intensive course, which means that 50% of the grade will be based on written work.
Grading
- one midterm (15%) and one final exam on lecture materials (15%) 30%
- laboratory work and worksheets 10%
- Drosophila project report 20%
- two short lab reports (5%, 10%) 15%
- Lab quizzes 5%
- Team exercises 10%
- Two short written assignments 10%
Materials
MATERIALS + SUPPLIES:
Required: iClickers will be used in class
RECOMMENDED READING:
Whatever genetics text you already have is fine
Registrar Notes:
SFU’s Academic Integrity web site http://students.sfu.ca/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating. Check out the site for more information and videos that help explain the issues in plain English.
Each student is responsible for his or her conduct as it affects the University community. Academic dishonesty, in whatever form, is ultimately destructive of the values of the University. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the University. http://www.sfu.ca/policies/gazette/student/s10-01.html
ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS