Summer 2018 - MBB 429 D100
RNA-mediated Gene Regulation (3)
Class Number: 4184
Delivery Method: In Person
Course Times + Location:
We, Fr 8:30 AM – 10:20 AM
AQ 5016, Burnaby
Exam Times + Location:
Aug 13, 2018
12:00 PM – 3:00 PM
AQ 5016, Burnaby
1 778 782-3448
Prerequisites:MBB 331 with a minimum grade of C.
RNA plays an important role in gene regulation. This course will explore recent primary literature studying the biochemistry of these processes.
Lecture topics will include, but are not limited to:
- RNA interference in plants and animals
- CRISPR bacterial antiviral defense
- Transcriptional and translational regulation - riboswitches, tmRNA, IRES elements, 6S RNA, etc.
- Post-transcriptional processing - editing, capping and splicing. Naturally occuring ribozymes.
- Class Presentation 30%
- Final Exam 30%
- Short Quizzes 30%
- Class Participation 10%
None. This course is based on primary literature (journal articles).
Supplementary material will be made available from selected texts or journal articles.
Bloomfield, Crothers and Tinoco. Nucleic Acids Structures, Properties and Functions, 2000. University Science Books.
Department Undergraduate Notes:
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ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS