Spring 2019 - MBB 321 D100

Intermediary Metabolism (3)

Class Number: 5052

Delivery Method: In Person


  • Course Times + Location:

    Mo, Fr 10:30 AM – 11:20 AM
    BLU 10021, Burnaby

    We 10:30 AM – 11:20 AM
    WMC 3210, Burnaby

  • Exam Times + Location:

    Apr 10, 2019
    3:30 PM – 6:30 PM
    EDB 7618, Burnaby

  • Instructor:

    Eunice Chin
    Office: B8220
  • Prerequisites:

    MBB 231, with a minimum grade of C.



The enzymes and intermediates of major catabolic and anabolic pathways. Their regulation and integration in health and disease states.


Lecture Topics:

  1. Review of bioenergetics, reaction mechanisms
  2. Catalysis, enzyme kinetics
  3. Carbohydrates: structure, glycogen metabolism
  4. Carbohydrates: glycolysis, citric acid cycle
  5. Carbohydrates: gluconeogenesis, pentose phosphate pathway
  6. Electron transport, oxidative phosphorylation
  7. Mitochondrial transport systems, lipid structure
  8. Lipids: beta oxidation, fatty acid biosynthesis
  9. Lipids: phospholipid biosynthesis, steroid metabolism
  10. Lipids: eicosanoid metabolism, amino acid metabolism
  11. Amino acids: urea cycle, nitrogen cycle
  12. Nucleotide biosynthesis and catabolism
  13. Metabolic regulation


  • Midterms 3 or 4 70%
  • Final 30%



Nelson and Cox, Lehninger Principles of Biochemistry, 7th edition, 2017. W.H. Freeman & Company.

Note:  An abridged version of the 7th edition containing relevant chapters will be available from the SFU Bookstore.

Department Undergraduate Notes:

  • Students are advised to review the plagiarism tutorial found at
  • For help with writing, learning and study strategies please contact the Student Learning Commons at
  • Students requiring accommodations as a result of a disability, must contact the Centre for Students with Disabilities (778-782-3112 or e-mail:  csdo@sfu.ca)

Registrar Notes:

SFU’s Academic Integrity web site http://www.sfu.ca/students/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating.  Check out the site for more information and videos that help explain the issues in plain English.

Each student is responsible for his or her conduct as it affects the University community.  Academic dishonesty, in whatever form, is ultimately destructive of the values of the University. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the University. http://www.sfu.ca/policies/gazette/student/s10-01.html