Simon Fraser University
Engaging the World

Course Outlines

Fall 2022 - MBB 321 D100

Intermediary Metabolism (3)

Class Number: 2178

Delivery Method: In Person

Overview

  • Course Times + Location:

    Sep 7 – Dec 6, 2022: Mon, Wed, Fri, 8:30–9:20 a.m.
    Burnaby

  • Exam Times + Location:

    Dec 10, 2022
    Sat, 7:00–10:00 p.m.
    Burnaby

  • Prerequisites:

    MBB 231, with a minimum grade of C.

Description

CALENDAR DESCRIPTION:

The enzymes and intermediates of major catabolic and anabolic pathways. Their regulation and integration in health and disease states.

COURSE DETAILS:

Lecture Topics:

  1. Review of bioenergetics, reaction mechanisms
  2. Catalysis, enzyme kinetics
  3. Carbohydrates: structure, glycogen metabolism
  4. Carbohydrates: glycolysis, citric acid cycle
  5. Carbohydrates: gluconeogenesis, pentose phosphate pathway
  6. Electron transport, oxidative phosphorylation
  7. Mitochondrial transport systems, lipid structure
  8. Lipids: beta oxidation, fatty acid biosynthesis
  9. Lipids: phospholipid biosynthesis, steroid metabolism
  10. Lipids: eicosanoid metabolism, amino acid metabolism
  11. Amino acids: urea cycle, nitrogen cycle
  12. Nucleotide biosynthesis and catabolism
  13. Metabolic regulation

Grading

  • Three 45-minute Midterm Exams (18% each) 54%
  • Two Cumulative Final Exams (18% each)* 36%
  • 15-minute Practice Quiz and Two Writing Skills Assignments 10%

NOTES:

*Cumulative exams are held on the same day during the scheduled Final Exam timeslot

Materials

REQUIRED READING:

Nelson and Cox, Lehninger Principles of Biochemistry, 8th edition, 2021. W.H. Freeman & Company.  Achieve for Lehninger Principles of Biochemistry (1-term access).
ISBN: 9781319230906

REQUIRED READING NOTES:

Your personalized Course Material list, including digital and physical textbooks, are available through the SFU Bookstore website by simply entering your Computing ID at: shop.sfu.ca/course-materials/my-personalized-course-materials.

Department Undergraduate Notes:


  • For help with writing, learning and study strategies please contact the Student Learning Commons at
    http://learningcommons.sfu.ca/
  • Students requiring accommodations as a result of a disability, must contact the Centre for Accessible Learning (778-782-3112 or e-mail:  caladmin@sfu.ca)

Registrar Notes:

ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS

SFU’s Academic Integrity website http://www.sfu.ca/students/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating. Check out the site for more information and videos that help explain the issues in plain English.

Each student is responsible for his or her conduct as it affects the university community. Academic dishonesty, in whatever form, is ultimately destructive of the values of the university. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the university. http://www.sfu.ca/policies/gazette/student/s10-01.html