Simon Fraser University
Engaging the World

Course Outlines

Fall 2023 - MBB 324 D100

Protein Biochemistry (3)

Class Number: 4326

Delivery Method: In Person

Overview

  • Course Times + Location:

    Sep 6 – Dec 5, 2023: Mon, Wed, Fri, 10:30–11:20 a.m.
    Burnaby

    Oct 10, 2023: Tue, 10:30–11:20 a.m.
    Burnaby

  • Exam Times + Location:

    Dec 6, 2023
    Wed, 8:30–11:30 a.m.
    Burnaby

  • Prerequisites:

    MBB 222 with a minimum grade of C.

Description

CALENDAR DESCRIPTION:

An exploration of the fundamental aspects of proteins; their chemical and physical nature, their synthesis, stability and turnover, as well as their structure and function. Methods of protein analysis and structure determination will be presented.

COURSE DETAILS:

Topics:

Noncovalent Interactions

Analysis of Primary, Secondary, Tertiary and Quaternary Structure

Post-translational Modifications

Fibrous Proteins

Methods of Structure Determination/Prediction

Protein Folding, Dynamics and Stability

Membrane Proteins

Protein interactions with Ligands, Drugs, and other Proteins

Enzyme Structure Function

Grading

  • Midterm 1 25%
  • Midterm 2 25%
  • Final (25% material since Midterm 2, 15% from Midterm 1&2 material) 40%
  • Assignments 10%

Materials

REQUIRED READING:

Introduction to Proteins: Structure, Function, and Motion, 2nd Ed, Kessel, Amit, Ben-Tal, Nir. 2018. CRC Press LLC. 
ISBN: 9781498747172

REQUIRED READING NOTES:

Your personalized Course Material list, including digital and physical textbooks, are available through the SFU Bookstore website by simply entering your Computing ID at: shop.sfu.ca/course-materials/my-personalized-course-materials.

Department Undergraduate Notes:


  • For help with writing, learning and study strategies please contact the Student Learning Commons at
    http://learningcommons.sfu.ca/
  • Students requiring accommodations as a result of a disability, must contact the Centre for Accessible Learning (778-782-3112 or e-mail:  caladmin@sfu.ca)

Registrar Notes:

ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS

SFU’s Academic Integrity website http://www.sfu.ca/students/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating. Check out the site for more information and videos that help explain the issues in plain English.

Each student is responsible for his or her conduct as it affects the university community. Academic dishonesty, in whatever form, is ultimately destructive of the values of the university. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the university. http://www.sfu.ca/policies/gazette/student/s10-01.html

RELIGIOUS ACCOMMODATION

Students with a faith background who may need accommodations during the semester are encouraged to assess their needs as soon as possible and review the Multifaith religious accommodations website. The page outlines ways they begin working toward an accommodation and ensure solutions can be reached in a timely fashion.