Fall 2023 - MBB 328 D100
Introduction to Microbial Pathogenesis (3)
Class Number: 4354
Delivery Method: In Person
Overview
-
Course Times + Location:
Sep 6 – Oct 6, 2023: Tue, Thu, 2:30–4:20 p.m.
BurnabyOct 11 – Dec 5, 2023: Tue, Thu, 2:30–4:20 p.m.
Burnaby -
Exam Times + Location:
Dec 14, 2023
Thu, 3:30–6:30 p.m.
Burnaby
-
Instructor:
Amy Lee
ahl23@sfu.ca
-
Prerequisites:
MBB 231 with a minimum grade of C.
Description
CALENDAR DESCRIPTION:
The molecular strategies that bacterial and viral pathogens use to colonize the human body and cause disease will be studied. Emphasis will be placed on the specific microbes and their virulence factors, secretion systems, toxins and surface adhesions. Strategies for combating microbial infections - antibiotics, antiviral agents and vaccines - will be discussed in detail. Students with credit for MBB 428 may not take this course for further credit.
COURSE DETAILS:
Description:
We will examine the molecular mechanisms by which microbial pathogens colonize the human body and cause disease. Emphasis will be placed on selected microbes and their structure/morphology, genetics, virulence factors, secretion systems, toxins and surface adhesions. Strategies for combating microbial infections, including antibiotics, antiviral agents and vaccines, will be discussed in detail. Students with credit for MBB 428 may not take this course for further credit.
Course Details:
Host immune response
Overview of virus structure
Selected viral pathogens:
- Polio virus
- Coronaviruses including SARS-CoV2
- Influenza virus
- Human immunodeficiency virus (HIV)
- Human papilloma virus (HPV)
- Herpes simplex virus (HSV)
Antiviral agents and resistance mechanisms
Selected bacterial pathogens:
- Listeria monocytogenes
- Streptococci, Enterococci, Staphylococcus aureus
- Pseudomonas aeruginosa
- pathogenic E. coli
- Klebsiella pneumoniae
Antibiotics and resistance mechanisms
Selected fungal pathogen & parasite
Vaccines
Human microbiota
Grading
- Two midterm exams and a cumulative final exam 80%
- Assignments 20%
NOTES:
Materials
RECOMMENDED READING:
Wilson, A.B. (2023). Introduction to Microbial Pathogenesis for Simon Fraser University ePDF.
ISBN: 9781394230235
REQUIRED READING NOTES:
Your personalized Course Material list, including digital and physical textbooks, are available through the SFU Bookstore website by simply entering your Computing ID at: shop.sfu.ca/course-materials/my-personalized-course-materials.
Department Undergraduate Notes:
- For help with writing, learning and study strategies please contact the Student Learning Commons at
http://learningcommons.sfu.ca/ - Students requiring accommodations as a result of a disability, must contact the Centre for Accessible Learning (778-782-3112 or e-mail: caladmin@sfu.ca)
Registrar Notes:
ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS
SFU’s Academic Integrity website http://www.sfu.ca/students/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating. Check out the site for more information and videos that help explain the issues in plain English.
Each student is responsible for his or her conduct as it affects the university community. Academic dishonesty, in whatever form, is ultimately destructive of the values of the university. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the university. http://www.sfu.ca/policies/gazette/student/s10-01.html
RELIGIOUS ACCOMMODATION
Students with a faith background who may need accommodations during the semester are encouraged to assess their needs as soon as possible and review the Multifaith religious accommodations website. The page outlines ways they begin working toward an accommodation and ensure solutions can be reached in a timely fashion.