Spring 2024 - MBB 443 D100
Protein Biogenesis and Degradation (3)
Class Number: 5488
Delivery Method: In Person
Overview
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Course Times + Location:
Jan 8 – Apr 12, 2024: Wed, Fri, 10:30 a.m.–12:20 p.m.
Burnaby -
Exam Times + Location:
Apr 20, 2024
Sat, 12:00–3:00 p.m.
Burnaby
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Instructor:
Michel Leroux
leroux@sfu.ca
1 778 782-5785
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Prerequisites:
MBB 321 and MBB 322, with a minimum grade of C.
Description
CALENDAR DESCRIPTION:
A consideration of protein biogenesis (folding, assembly, and targeting to cellular compartments), modification, and degradation, and their roles in protein and cellular function.
COURSE DETAILS:
Course Description The central dogma of molecular biology (DNA --› RNA --› PROTEIN) underscores two fundamental biological processes, transcription and translation, that are essential to life. Protein biogenesis (folding, assembly, targeting to the proper cellular compartment), and protein degradation represent two other equally important cellular activities. The emphasis in this course will be to review the literature on protein biogenesis and degradation, and explore the new and exciting developments that are just starting to uncover how mechanistically complex these processes are.
Grading
- Midterm I 25%
- Oral Presentation 15%
- Term Paper 20%
- Midterm II 40%
Materials
MATERIALS + SUPPLIES:
None.
REQUIRED READING:
None.
RECOMMENDED READING:
None.
REQUIRED READING NOTES:
Your personalized Course Material list, including digital and physical textbooks, are available through the SFU Bookstore website by simply entering your Computing ID at: shop.sfu.ca/course-materials/my-personalized-course-materials.
Department Undergraduate Notes:
- For help with writing, learning and study strategies please contact the Student Learning Commons at
http://learningcommons.sfu.ca/ - Students requiring accommodations as a result of a disability, must contact the Centre for Accessible Learning (778-782-3112 or e-mail: caladmin@sfu.ca)
Registrar Notes:
ACADEMIC INTEGRITY: YOUR WORK, YOUR SUCCESS
SFU’s Academic Integrity website http://www.sfu.ca/students/academicintegrity.html is filled with information on what is meant by academic dishonesty, where you can find resources to help with your studies and the consequences of cheating. Check out the site for more information and videos that help explain the issues in plain English.
Each student is responsible for his or her conduct as it affects the university community. Academic dishonesty, in whatever form, is ultimately destructive of the values of the university. Furthermore, it is unfair and discouraging to the majority of students who pursue their studies honestly. Scholarly integrity is required of all members of the university. http://www.sfu.ca/policies/gazette/student/s10-01.html