J. Thewalt Lab

NMR magnet in our lab

Research

Click on one of the links below to read about our projects.

Laurdan

Sterols

Sphingomyelin and Cholesterol

Sphingomyelin and Ceramide

List of Publications

GUV dyed with fluorescence probe DiIC12

Laurdan

Even at low concentrations, fluorescence probes can affect the miscibility transition temperature of lipid membranes. This project studies the effects of adding the probe Laurdan.

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Homer Simpson eating a burger

Sterols

There are slight structural differences between cholesterol and other sterols. These differences are utilized to help us understand cholesterol better.

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Cholesterol intercalated into a lipid bilayer

Sphingomyelin and Cholesterol

These lipids are the major components of putative lipid raft. This project studies the temperature- and concentration-dependent phase behavior of palmitoyl sphingomyelin and cholesterol.

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The grim reaper

Sphingomyelin and Ceramide

These lipids are involved in apoptosis - or programmed cell death. This project studies the temperature- and concentration-dependent phase behavior of palmityol sphingomyelin and ceramide.

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